Mechanisms of inactivation of the p16INK4a gene in leiomyosarcoma of soft tissue: Decreased p 16 expression correlates with promoter methylation and poor prognosis

Ken Ichi Kawaguchi, Yoshinao Oda, Tsuyoshi Saito, Hidetaka Yamamoto, Sadafumi Tamiya, Tomonari Takahira, Kimitaka Miyajima, Yukihide Iwamoto, Masazumi Tsuneyoshi

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Biochemistry, Genetics and Molecular Biology