Mechanisms of maintaining genetic stability by homologous recombination

Yoshizumi Ishino, Tatsuya Nishino, Kosuke Morikawa

Research output: Contribution to journalReview articlepeer-review

22 Citations (Scopus)

Abstract

An overview of the structural and functional aspects of many important proteins, most of which are involved in recombinatorial repair processes in Bacteria and Archae is given. In general, DNA processing proteins contain multiple structural domains, each with a distinct function. Furthermore, these proteins contain versatile structural modules to interact with DNA and other partner proteins. The data given provide detailed insights into how the proteins recognize and process DNA with irregular and complex structures during recombination repair.

Original languageEnglish
Pages (from-to)324-339
Number of pages16
JournalChemical Reviews
Volume106
Issue number2
DOIs
Publication statusPublished - Feb 1 2006

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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