Medial temporal lobe epilepsy associated with cortical dysplasia extending from the medial temporal lobe to the fornix: A case report

Takato Morioka, Nobutaka Mukae, Tetsuro Sayama, Takeshi Hamamura, Asako Nomoto, Kuniko Yamamoto, Tomomi Kido, Tatsumi Yamaguchi, Satoshi O. Suzuki, Tomio Sasaki

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report a case of lesional medial temporal lobe epilepsy (TLE) associated with cortical dysplasia extending from the right medial temporal lobe to the fornix via the basal and medial aspects of the frontal lobe and septum pellucidum. A 23-year-old man had had medically intractable psychomotor seizures since 11 years of age. Interictal EEG demonstrated paroxysmal activities in the right temporal region, and functional imaging by positron emission tomography with [18F] fluorodeoxyglucose revealed a functional deficit zone in the apex and medial part of the right temporal lobe. An intraoperative electrocorticogram demonstrated frequent paroxysmal activities in the medial temporal lobe. An anterior temporal lobectomy was performed, with an additional hippocampectomy including the focus of the paroxysmal activities on the intraoperative hippocampal EEG. Postoperatively, he became seizure-free. The surgical strategies forintractable TLE with widely distributed cortical dysplasia lesion are discussed.

Original languageEnglish
Pages (from-to)10-18
Number of pages9
JournalEpilepsy and Seizure
Volume3
Issue number1
DOIs
Publication statusPublished - 2010

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

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