TY - JOUR
T1 - Mediastinal paraganglioma
AU - Takashima, Yoko
AU - Kamitani, Takeshi
AU - Kawanami, Satoshi
AU - Nagao, Michinobu
AU - Yonezawa, Masato
AU - Yamasaki, Yuzo
AU - Baba, Shingo
AU - Yabuuchi, Hidetake
AU - Hida, Tomoyuki
AU - Kohashi, Kenichi
AU - Nakamura, Katsuya
AU - Sonoda, Hiromichi
AU - Oda, Yoshinao
AU - Honda, Hiroshi
PY - 2015/7/25
Y1 - 2015/7/25
N2 - We present a case of mediastinal paraganglioma with radiologic–pathologic correlation. A 48-year-old woman was found incidentally to have a middle mediastinal mass on CT. The mass showed iso-signal intensity compared to that of muscle on T1-weighted images and high signal intensity on T2-weighted images. The lesion showed intermediate intensity on diffusion-weighted imaging, and its apparent diffusion coefficient was 1.72 × 10−3 mm2/s. A contrast-enhanced dynamic study revealed a rapid peak and washout enhancement pattern. 18F-FDG-PET revealed abnormal uptake in the mediastinal tumor with a maximal standardized uptake value of 7.88. 123I-meta-iodobenzylguanidine scintigraphy also showed abnormal uptake in the tumor. These findings corresponded to the hypervascularity, rich stroma, low nuclear/cytoplasmic ratio, and nest-forming proliferation of tumor cells with positive neuroendocrine markers.
AB - We present a case of mediastinal paraganglioma with radiologic–pathologic correlation. A 48-year-old woman was found incidentally to have a middle mediastinal mass on CT. The mass showed iso-signal intensity compared to that of muscle on T1-weighted images and high signal intensity on T2-weighted images. The lesion showed intermediate intensity on diffusion-weighted imaging, and its apparent diffusion coefficient was 1.72 × 10−3 mm2/s. A contrast-enhanced dynamic study revealed a rapid peak and washout enhancement pattern. 18F-FDG-PET revealed abnormal uptake in the mediastinal tumor with a maximal standardized uptake value of 7.88. 123I-meta-iodobenzylguanidine scintigraphy also showed abnormal uptake in the tumor. These findings corresponded to the hypervascularity, rich stroma, low nuclear/cytoplasmic ratio, and nest-forming proliferation of tumor cells with positive neuroendocrine markers.
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U2 - 10.1007/s11604-015-0436-z
DO - 10.1007/s11604-015-0436-z
M3 - Article
C2 - 26025611
AN - SCOPUS:84937972073
SN - 1867-1071
VL - 33
SP - 433
EP - 436
JO - Japanese Journal of Radiology
JF - Japanese Journal of Radiology
IS - 7
ER -