Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance

Biochemistry, Genetics and Molecular Biology

• Kinase 100%
• Insulin 75%
• Phosphatidylinositol 75%
• Membrane 25%
• Mitogen-Activated Protein Kinase 16%
• Phosphorylation 16%
• Insulin Resistance 16%
• Insulin Signaling 16%
• Biological Activity 8%
• Wild Type 8%
• Protein Biosynthesis 8%
• Signal Transduction 8%
• Cell Membrane 8%
• Adipocyte 8%
• P21 8%
• Immunoprecipitation 8%
• Adenoviridae 8%
• Tyrosine Phosphorylation 8%
• Transfer Gene 8%
• Glucose Transport 8%
• Myc 8%
• Platelet-Derived Growth Factor 8%
• 3T3-L1 8%
• Insulin Receptor 8%
• Glycogenesis 8%
• Glycogen Synthase 8%

Medicine and Dentistry

• Insulin 75%
• Phosphoinositide 3-Kinase 75%
• Membrane 25%
• Mitogen-Activated Protein Kinase 25%
• Phosphorylation 16%
• Biological Product 16%
• Insulin Signaling 16%
• Insulin Resistance 16%
• Ras 16%
• Cells 8%
• Signal Transduction 8%
• Protein Synthesis 8%
• Stimulation 8%
• Biological Activity 8%
• Phosphotransferase 8%
• P21 8%
• Desensitization 8%
• Adenoviridae 8%
• Adipocyte 8%
• Cell Membrane 8%
• Protein Phosphorylation 8%
• Gene Transfer 8%
• Deoxyglucose 8%
• Glucose Uptake 8%
• Platelet Derived Growth Factor 8%
• 3T3-L1 8%
• Glycogen Synthesis 8%
• Glycogen Synthase 8%
• Insulin Receptor 8%
• S6 Kinase 8%