Supramolecular self-assemblies of complementary components 1 or 2 (calixarene derivatives with two or four 2,6-diaminopyridine units, respectively) and 3 (5,5-dialkyl barbituric acids) in chloroform-acetonitrile solution were confirmed by 1H NMR spectroscopy and light scattering. While derivative 1 interacts with 3 only after addition of Na+ cation, which disrupts intramolecular hydrogen bonds, compound 2 creates a complex with 3 even without the presence of Na+ cation, indicating much weaker intramolecular bonds in this derivative.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry