Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review

Yukako Mokutani, Taishi Hata, Yuichiro Miyake, Hideki Kuroda, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Primary hepatic angiosarcoma is a rare type of tumor with a poor prognosis. To the best of our knowledge, curative surgery of a metastatic gastrointestinal angiosarcoma from a hepatic angiosarcoma has not been reported previously. In the present report, a case of colonic metastasis from a primary hepatic angiosarcoma is discussed. A rapidly growing mass was identified in the liver of an 84-year-old Japanese male who underwent a subsegmentectomy of the liver. Microscopic examination determined that the mass was an angiosarcoma composed of sheets of spindle cells. Immunohistochemical studies confirmed the diagnosis with positive CD31 staining, which indicated the endothelial nature of the malignancy. A total of 14 months following surgery, the patient did not exhibit any symptoms; however, follow-up positron emission tomography and computed tomography images revealed a mass in the cecum. The patient underwent an ileocolectomy, and the microscopic and immunohistochemical findings indicated that the mass was a metastasized colorectal angiosarcoma. At a 4-year post-surgery follow-up appointment the patient was alive with no evidence of recurrence or metastasis.

Original languageEnglish
Pages (from-to)2765-2769
Number of pages5
JournalOncology Letters
Volume13
Issue number4
DOIs
Publication statusPublished - Apr 2017

Fingerprint

Hemangiosarcoma
Colon
Neoplasm Metastasis
Liver
Cecum
Neoplasms
Appointments and Schedules
Staining and Labeling
Recurrence

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Metastasis from a primary hepatic angiosarcoma to the colon : A case report and literature review. / Mokutani, Yukako; Hata, Taishi; Miyake, Yuichiro; Kuroda, Hideki; Takahashi, Hidekazu; Haraguchi, Naotsugu; Nishimura, Junichi; Mizushima, Tsunekazu; Yamamoto, Hirofumi; Doki, Yuichiro; Mori, Masaki.

In: Oncology Letters, Vol. 13, No. 4, 04.2017, p. 2765-2769.

Research output: Contribution to journalArticle

Mokutani, Y, Hata, T, Miyake, Y, Kuroda, H, Takahashi, H, Haraguchi, N, Nishimura, J, Mizushima, T, Yamamoto, H, Doki, Y & Mori, M 2017, 'Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review', Oncology Letters, vol. 13, no. 4, pp. 2765-2769. https://doi.org/10.3892/ol.2017.5755
Mokutani Y, Hata T, Miyake Y, Kuroda H, Takahashi H, Haraguchi N et al. Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review. Oncology Letters. 2017 Apr;13(4):2765-2769. https://doi.org/10.3892/ol.2017.5755
Mokutani, Yukako ; Hata, Taishi ; Miyake, Yuichiro ; Kuroda, Hideki ; Takahashi, Hidekazu ; Haraguchi, Naotsugu ; Nishimura, Junichi ; Mizushima, Tsunekazu ; Yamamoto, Hirofumi ; Doki, Yuichiro ; Mori, Masaki. / Metastasis from a primary hepatic angiosarcoma to the colon : A case report and literature review. In: Oncology Letters. 2017 ; Vol. 13, No. 4. pp. 2765-2769.
@article{f8c81e9f5b4043c38e5ef657c414a06b,
title = "Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review",
abstract = "Primary hepatic angiosarcoma is a rare type of tumor with a poor prognosis. To the best of our knowledge, curative surgery of a metastatic gastrointestinal angiosarcoma from a hepatic angiosarcoma has not been reported previously. In the present report, a case of colonic metastasis from a primary hepatic angiosarcoma is discussed. A rapidly growing mass was identified in the liver of an 84-year-old Japanese male who underwent a subsegmentectomy of the liver. Microscopic examination determined that the mass was an angiosarcoma composed of sheets of spindle cells. Immunohistochemical studies confirmed the diagnosis with positive CD31 staining, which indicated the endothelial nature of the malignancy. A total of 14 months following surgery, the patient did not exhibit any symptoms; however, follow-up positron emission tomography and computed tomography images revealed a mass in the cecum. The patient underwent an ileocolectomy, and the microscopic and immunohistochemical findings indicated that the mass was a metastasized colorectal angiosarcoma. At a 4-year post-surgery follow-up appointment the patient was alive with no evidence of recurrence or metastasis.",
author = "Yukako Mokutani and Taishi Hata and Yuichiro Miyake and Hideki Kuroda and Hidekazu Takahashi and Naotsugu Haraguchi and Junichi Nishimura and Tsunekazu Mizushima and Hirofumi Yamamoto and Yuichiro Doki and Masaki Mori",
year = "2017",
month = "4",
doi = "10.3892/ol.2017.5755",
language = "English",
volume = "13",
pages = "2765--2769",
journal = "Oncology Letters",
issn = "1792-1074",
publisher = "Spandidos Publications",
number = "4",

}

TY - JOUR

T1 - Metastasis from a primary hepatic angiosarcoma to the colon

T2 - A case report and literature review

AU - Mokutani, Yukako

AU - Hata, Taishi

AU - Miyake, Yuichiro

AU - Kuroda, Hideki

AU - Takahashi, Hidekazu

AU - Haraguchi, Naotsugu

AU - Nishimura, Junichi

AU - Mizushima, Tsunekazu

AU - Yamamoto, Hirofumi

AU - Doki, Yuichiro

AU - Mori, Masaki

PY - 2017/4

Y1 - 2017/4

N2 - Primary hepatic angiosarcoma is a rare type of tumor with a poor prognosis. To the best of our knowledge, curative surgery of a metastatic gastrointestinal angiosarcoma from a hepatic angiosarcoma has not been reported previously. In the present report, a case of colonic metastasis from a primary hepatic angiosarcoma is discussed. A rapidly growing mass was identified in the liver of an 84-year-old Japanese male who underwent a subsegmentectomy of the liver. Microscopic examination determined that the mass was an angiosarcoma composed of sheets of spindle cells. Immunohistochemical studies confirmed the diagnosis with positive CD31 staining, which indicated the endothelial nature of the malignancy. A total of 14 months following surgery, the patient did not exhibit any symptoms; however, follow-up positron emission tomography and computed tomography images revealed a mass in the cecum. The patient underwent an ileocolectomy, and the microscopic and immunohistochemical findings indicated that the mass was a metastasized colorectal angiosarcoma. At a 4-year post-surgery follow-up appointment the patient was alive with no evidence of recurrence or metastasis.

AB - Primary hepatic angiosarcoma is a rare type of tumor with a poor prognosis. To the best of our knowledge, curative surgery of a metastatic gastrointestinal angiosarcoma from a hepatic angiosarcoma has not been reported previously. In the present report, a case of colonic metastasis from a primary hepatic angiosarcoma is discussed. A rapidly growing mass was identified in the liver of an 84-year-old Japanese male who underwent a subsegmentectomy of the liver. Microscopic examination determined that the mass was an angiosarcoma composed of sheets of spindle cells. Immunohistochemical studies confirmed the diagnosis with positive CD31 staining, which indicated the endothelial nature of the malignancy. A total of 14 months following surgery, the patient did not exhibit any symptoms; however, follow-up positron emission tomography and computed tomography images revealed a mass in the cecum. The patient underwent an ileocolectomy, and the microscopic and immunohistochemical findings indicated that the mass was a metastasized colorectal angiosarcoma. At a 4-year post-surgery follow-up appointment the patient was alive with no evidence of recurrence or metastasis.

UR - http://www.scopus.com/inward/record.url?scp=85015313232&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85015313232&partnerID=8YFLogxK

U2 - 10.3892/ol.2017.5755

DO - 10.3892/ol.2017.5755

M3 - Article

AN - SCOPUS:85015313232

VL - 13

SP - 2765

EP - 2769

JO - Oncology Letters

JF - Oncology Letters

SN - 1792-1074

IS - 4

ER -