Methamphetamine and amphetamine concentrations in postmortem rabbit tissues

T. Nagata, K. Kimura, K. Hara, K. Kudo

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

The feasibility of detecting methamphetamine and its major metabolite, amphetamine, in postmortem tissues over a 2-year period was examined. It is important to determine if the abuse and toxic effects of drugs can be proved from evidence found in decayed, submerged, or stained tissue materials. The blood, urine, liver, skeletal muscle, skin and extremity bones from rabbits given methamphetamine intravenously were kept at room temperature, under 4 different conditions: sealed in a test tube, dried in the open air, submerged in tap water and stained on gauze. Methamphetamine was present in all the samples, with slight change in concentration in case of sealed and air dried tissues. Changes varied in bones kept in water. There were considerable decreases in methamphetamine in blood and urine stains. Despite long term storage, drug abuse and/or toxicity could be determined, in all tissues examined.

Original languageEnglish
Pages (from-to)39-47
Number of pages9
JournalForensic Science International
Volume48
Issue number1
DOIs
Publication statusPublished - Nov 1990

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

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