Methyl-transfer reaction to alkylthiol catalyzed by a simple vitamin B 12 model complex using zinc powder

Ling Pan, Keishiro Tahara, Takahiro Masuko, Yoshio Hisaeda

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9 Citations (Scopus)

Abstract

The catalytic methyl-transfer reaction from methyl tosylate to 1-octanethiol was carried out in the presence of a simple vitamin B12 model complex, [Co(III){(C2C3)(DO)(DOH)pn}Br 2], with zinc powder as the reducing reagent at 50°C. Such a catalytic reaction proceeded via the formation and dissociation of a cobalt-carbon bond in the simple vitamin B12 model complex under non-enzymatic conditions. The mechanism for the methyl-transfer reaction was investigated by electronic and mass spectroscopies. The Co(I) species, which is generated from the reduction of the catalyst by the zinc powder, and its methylated CH3-Co complex were found to be indispensable intermediates.

Original languageEnglish
Pages (from-to)194-199
Number of pages6
JournalInorganica Chimica Acta
Volume368
Issue number1
DOIs
Publication statusPublished - Mar 15 2011

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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