Micro- and nanoscopic biotribological behaviours in natural synovial joints and artificial joints

T. Murakami, Yoshinori Sawae, Kazuhiro Nakashima, S. Yarimitsu, T. Sato

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

To maintain low friction and low wear in natural synovial joints and joint prostheses with artificial cartilage, adsorbed film formation at micro- and nanoscopic levels appears to play an important role in mixed or boundary lubrication regime where local direct contact occurs. In natural synovial joints, the lubricating gel film is likely to preserve low friction and to protect the bulk cartilage even after the removal of the adsorbed film. For poly (vinyl alcohol) (PVA) hydrogel as artificial cartilage without lubricating gel layer, the adsorbed film is a single protective barrier. In the previous researches on the rubbing pair of PVA against itself or glass plate, the coexistence of albumin (A) and γ-globulin (G) as A:G = 1: 2 at total protein concentration of 2.1 wt% in hyaluronate solution showed the lowest wear. In this study, in situ observation of adsorption of proteins was conducted to clarify the dynamic changes in adsorptional behaviours in lubricants containing different protein constituents. In the mixed lubrication regime, the coexistence of albumin and γ-globulin as A:G = 1:2 showed the lowest friction. The role of appropriate constituents of proteins is discussed on low friction and low wear at micro- and nanoscopic levels on the basis of previous and present results.

Original languageEnglish
Pages (from-to)237-245
Number of pages9
JournalProceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology
Volume221
Issue number3
DOIs
Publication statusPublished - May 1 2007

Fingerprint

cartilage
Cartilage
friction
globulins
Friction
proteins
Proteins
Globulins
Wear of materials
lubrication
albumins
Lubrication
Albumins
Gels
Joint prostheses
gels
boundary lubrication
Hydrogel
lubricants
Hydrogels

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films

Cite this

Micro- and nanoscopic biotribological behaviours in natural synovial joints and artificial joints. / Murakami, T.; Sawae, Yoshinori; Nakashima, Kazuhiro; Yarimitsu, S.; Sato, T.

In: Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology, Vol. 221, No. 3, 01.05.2007, p. 237-245.

Research output: Contribution to journalArticle

@article{8c3a678ea5a64f8aba554ed51318fb82,
title = "Micro- and nanoscopic biotribological behaviours in natural synovial joints and artificial joints",
abstract = "To maintain low friction and low wear in natural synovial joints and joint prostheses with artificial cartilage, adsorbed film formation at micro- and nanoscopic levels appears to play an important role in mixed or boundary lubrication regime where local direct contact occurs. In natural synovial joints, the lubricating gel film is likely to preserve low friction and to protect the bulk cartilage even after the removal of the adsorbed film. For poly (vinyl alcohol) (PVA) hydrogel as artificial cartilage without lubricating gel layer, the adsorbed film is a single protective barrier. In the previous researches on the rubbing pair of PVA against itself or glass plate, the coexistence of albumin (A) and γ-globulin (G) as A:G = 1: 2 at total protein concentration of 2.1 wt{\%} in hyaluronate solution showed the lowest wear. In this study, in situ observation of adsorption of proteins was conducted to clarify the dynamic changes in adsorptional behaviours in lubricants containing different protein constituents. In the mixed lubrication regime, the coexistence of albumin and γ-globulin as A:G = 1:2 showed the lowest friction. The role of appropriate constituents of proteins is discussed on low friction and low wear at micro- and nanoscopic levels on the basis of previous and present results.",
author = "T. Murakami and Yoshinori Sawae and Kazuhiro Nakashima and S. Yarimitsu and T. Sato",
year = "2007",
month = "5",
day = "1",
doi = "10.1243/13506501JET245",
language = "English",
volume = "221",
pages = "237--245",
journal = "Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology",
issn = "1350-6501",
publisher = "SAGE Publications Ltd",
number = "3",

}

TY - JOUR

T1 - Micro- and nanoscopic biotribological behaviours in natural synovial joints and artificial joints

AU - Murakami, T.

AU - Sawae, Yoshinori

AU - Nakashima, Kazuhiro

AU - Yarimitsu, S.

AU - Sato, T.

PY - 2007/5/1

Y1 - 2007/5/1

N2 - To maintain low friction and low wear in natural synovial joints and joint prostheses with artificial cartilage, adsorbed film formation at micro- and nanoscopic levels appears to play an important role in mixed or boundary lubrication regime where local direct contact occurs. In natural synovial joints, the lubricating gel film is likely to preserve low friction and to protect the bulk cartilage even after the removal of the adsorbed film. For poly (vinyl alcohol) (PVA) hydrogel as artificial cartilage without lubricating gel layer, the adsorbed film is a single protective barrier. In the previous researches on the rubbing pair of PVA against itself or glass plate, the coexistence of albumin (A) and γ-globulin (G) as A:G = 1: 2 at total protein concentration of 2.1 wt% in hyaluronate solution showed the lowest wear. In this study, in situ observation of adsorption of proteins was conducted to clarify the dynamic changes in adsorptional behaviours in lubricants containing different protein constituents. In the mixed lubrication regime, the coexistence of albumin and γ-globulin as A:G = 1:2 showed the lowest friction. The role of appropriate constituents of proteins is discussed on low friction and low wear at micro- and nanoscopic levels on the basis of previous and present results.

AB - To maintain low friction and low wear in natural synovial joints and joint prostheses with artificial cartilage, adsorbed film formation at micro- and nanoscopic levels appears to play an important role in mixed or boundary lubrication regime where local direct contact occurs. In natural synovial joints, the lubricating gel film is likely to preserve low friction and to protect the bulk cartilage even after the removal of the adsorbed film. For poly (vinyl alcohol) (PVA) hydrogel as artificial cartilage without lubricating gel layer, the adsorbed film is a single protective barrier. In the previous researches on the rubbing pair of PVA against itself or glass plate, the coexistence of albumin (A) and γ-globulin (G) as A:G = 1: 2 at total protein concentration of 2.1 wt% in hyaluronate solution showed the lowest wear. In this study, in situ observation of adsorption of proteins was conducted to clarify the dynamic changes in adsorptional behaviours in lubricants containing different protein constituents. In the mixed lubrication regime, the coexistence of albumin and γ-globulin as A:G = 1:2 showed the lowest friction. The role of appropriate constituents of proteins is discussed on low friction and low wear at micro- and nanoscopic levels on the basis of previous and present results.

UR - http://www.scopus.com/inward/record.url?scp=34250679791&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34250679791&partnerID=8YFLogxK

U2 - 10.1243/13506501JET245

DO - 10.1243/13506501JET245

M3 - Article

AN - SCOPUS:34250679791

VL - 221

SP - 237

EP - 245

JO - Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology

JF - Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology

SN - 1350-6501

IS - 3

ER -