[Microbiological and clinical features of nine cases with nocardial infections].

Yukiko Maki, Yujiro Uchida, Nobuhisa Monji, Tomomi Mochimaru, Yuiko Morokuma, Takato Karashima, Makiko Kiyosuke, Masako Fujise, Fujiko Eto, Noriko Miyake, Nobuyuki Shimono, Yuzo Kayamori, Dongchon Kang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Following recent advance in medical technology, the increase of immunocompromised patients results in an increase of opportunistic infections such as nocardiosis. However, little is known about relationships between clinical features of nocardial infections and each Nocardia species, especially newly identified ones. Therefore, we identified clinical isolates of Nocardia species by genetic methods and analyzed clinical features of nocardiosis. Nine clinical isolates were obtained in Kyushu University Hospital from 2005 to 2008. Six different Nocardia species were identified by 16Sr RNA: Nocardiafarcinia (n=2), Nocardia brasiliensis (n=2), Nocardia cyriacigeorgica (n=2), Nocardia transvalensis (n=1), Nocardia araoensis (n=1) and Nocardia testacea (n=1). The underlying diseases of 9 patients were pulmonary diseases(n=5), malignant diseases(n=3), collagen diseases(n=1) or primary immunodeficiency diseases (n=l). According to antimicrobial susceptibility testing, none of them was resistant to minocycline or linezolid. Among seven isolates from respiratory specimens, one was resistant to imipenem, sulfamethoxazole/trimethoprim and amikacin, two were to ciprofloxacin. Three species identified recently (N cyriacigeorgica, N. araoensis and N. testacea) were involved in this study and most of them were considered as infectious pathogens to human. These data suggested the identification of Nocardia to the species level and susceptibility testing were important for diagnosis as infectious diseases and treatments.

Original languageEnglish
Pages (from-to)213-218
Number of pages6
JournalRinsho byori. The Japanese journal of clinical pathology
Volume59
Issue number3
Publication statusPublished - Mar 2011

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Nocardia
Nocardia Infections
Infection
Linezolid
Collagen Diseases
Minocycline
Amikacin
Imipenem
Opportunistic Infections
Sulfamethoxazole Drug Combination Trimethoprim
Immunocompromised Host
Ciprofloxacin
Lung Diseases
Communicable Diseases
RNA
Technology

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Maki, Y., Uchida, Y., Monji, N., Mochimaru, T., Morokuma, Y., Karashima, T., ... Kang, D. (2011). [Microbiological and clinical features of nine cases with nocardial infections]. Rinsho byori. The Japanese journal of clinical pathology, 59(3), 213-218.

[Microbiological and clinical features of nine cases with nocardial infections]. / Maki, Yukiko; Uchida, Yujiro; Monji, Nobuhisa; Mochimaru, Tomomi; Morokuma, Yuiko; Karashima, Takato; Kiyosuke, Makiko; Fujise, Masako; Eto, Fujiko; Miyake, Noriko; Shimono, Nobuyuki; Kayamori, Yuzo; Kang, Dongchon.

In: Rinsho byori. The Japanese journal of clinical pathology, Vol. 59, No. 3, 03.2011, p. 213-218.

Research output: Contribution to journalArticle

Maki, Y, Uchida, Y, Monji, N, Mochimaru, T, Morokuma, Y, Karashima, T, Kiyosuke, M, Fujise, M, Eto, F, Miyake, N, Shimono, N, Kayamori, Y & Kang, D 2011, '[Microbiological and clinical features of nine cases with nocardial infections].', Rinsho byori. The Japanese journal of clinical pathology, vol. 59, no. 3, pp. 213-218.
Maki Y, Uchida Y, Monji N, Mochimaru T, Morokuma Y, Karashima T et al. [Microbiological and clinical features of nine cases with nocardial infections]. Rinsho byori. The Japanese journal of clinical pathology. 2011 Mar;59(3):213-218.
Maki, Yukiko ; Uchida, Yujiro ; Monji, Nobuhisa ; Mochimaru, Tomomi ; Morokuma, Yuiko ; Karashima, Takato ; Kiyosuke, Makiko ; Fujise, Masako ; Eto, Fujiko ; Miyake, Noriko ; Shimono, Nobuyuki ; Kayamori, Yuzo ; Kang, Dongchon. / [Microbiological and clinical features of nine cases with nocardial infections]. In: Rinsho byori. The Japanese journal of clinical pathology. 2011 ; Vol. 59, No. 3. pp. 213-218.
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