Microchannel-assisted preparation of polyion complex vesicles and real-time observation of their dynamic responses to external electric fields

D. Sueyoshi, Akihiro Kishimura, H. Oana, Y. Anraku, M. Takai, M. Washizu, K. Kataoka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Polyion complex (PIC) vesicles, PICsomes, are polymeric vesicles which can form through electrostatic interaction between an oppositely charged polyethylene glycol (PEG)-based block ionomers and homo ionomers. In this study, for further utilization and understanding of their characteristic dynamic properties in aqueous media, we conducted real-time observation of their responses to external electric fields (EFs). This observation was facilitated by a newly designed microfluidic channel, which enabled preparation of micrometer-sized PICsomes and observation of their behaviors under controlled EF conditions. Their non-trivial responses and their EF dependency were carefully evaluated, and some dynamic behaviors were observed in several EF conditions.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages1882-1884
Number of pages3
ISBN (Electronic)9780979806476
Publication statusPublished - Jan 1 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/1410/30/14

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All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Sueyoshi, D., Kishimura, A., Oana, H., Anraku, Y., Takai, M., Washizu, M., & Kataoka, K. (2014). Microchannel-assisted preparation of polyion complex vesicles and real-time observation of their dynamic responses to external electric fields. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 1882-1884). (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014). Chemical and Biological Microsystems Society.