TY - GEN
T1 - Microchannel-assisted preparation of polyion complex vesicles and real-time observation of their dynamic responses to external electric fields
AU - Sueyoshi, D.
AU - Kishimura, Akihiro
AU - Oana, H.
AU - Anraku, Y.
AU - Takai, M.
AU - Washizu, M.
AU - Kataoka, K.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Polyion complex (PIC) vesicles, PICsomes, are polymeric vesicles which can form through electrostatic interaction between an oppositely charged polyethylene glycol (PEG)-based block ionomers and homo ionomers. In this study, for further utilization and understanding of their characteristic dynamic properties in aqueous media, we conducted real-time observation of their responses to external electric fields (EFs). This observation was facilitated by a newly designed microfluidic channel, which enabled preparation of micrometer-sized PICsomes and observation of their behaviors under controlled EF conditions. Their non-trivial responses and their EF dependency were carefully evaluated, and some dynamic behaviors were observed in several EF conditions.
AB - Polyion complex (PIC) vesicles, PICsomes, are polymeric vesicles which can form through electrostatic interaction between an oppositely charged polyethylene glycol (PEG)-based block ionomers and homo ionomers. In this study, for further utilization and understanding of their characteristic dynamic properties in aqueous media, we conducted real-time observation of their responses to external electric fields (EFs). This observation was facilitated by a newly designed microfluidic channel, which enabled preparation of micrometer-sized PICsomes and observation of their behaviors under controlled EF conditions. Their non-trivial responses and their EF dependency were carefully evaluated, and some dynamic behaviors were observed in several EF conditions.
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M3 - Conference contribution
AN - SCOPUS:84941671367
T3 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
SP - 1882
EP - 1884
BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PB - Chemical and Biological Microsystems Society
T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Y2 - 26 October 2014 through 30 October 2014
ER -