Micropatterned saccharide display on the silicon surface

Hajime Sato, Yoshiko Miura, Nagahiro Saito, Kazukiyo Kobayashi, Osamu Takai

Research output: Contribution to conferencePaper

Abstract

The immobilization and the micro-patterning of biomolecules on the solid surfaces are paid much attention for the application of biomaterials, and biosensors. Micro-patterned carbohydrates on solid surfaces are useful to analyze carbohydrate-protein interactions and to fabricate the scaffolds of cell cultivation. We have proposed a new method for micro-patterned carbohydrate display. The micropattern composed of hydrophobic and electrostatically positive regions were fabricated by methyl and amino terminated self-assembled monolayers (SAM). The patterned substrates were incubated in two types of aqueous solutions of PVLA and Heparin, in this order. The PVLA and Heparin site-selectively adsorbed on methyl and amino terminated SAMs, respectively. It indicated that the two dimensional matrix of PVLA and Heparin can be fabricated on the micro-patterned substrate. The micropatterning of two different components on one substrate enables two different biomacromolecules to be self-assembled into micro pattern.

Original languageEnglish
Number of pages1
Publication statusPublished - Dec 1 2005
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period5/25/055/27/05

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Carbohydrates
Display devices
Silicon
Substrates
Biomolecules
Self assembled monolayers
Scaffolds (biology)
Biosensors
Biomaterials
Proteins
Heparin

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Sato, H., Miura, Y., Saito, N., Kobayashi, K., & Takai, O. (2005). Micropatterned saccharide display on the silicon surface. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.

Micropatterned saccharide display on the silicon surface. / Sato, Hajime; Miura, Yoshiko; Saito, Nagahiro; Kobayashi, Kazukiyo; Takai, Osamu.

2005. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.

Research output: Contribution to conferencePaper

Sato, H, Miura, Y, Saito, N, Kobayashi, K & Takai, O 2005, 'Micropatterned saccharide display on the silicon surface', Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan, 5/25/05 - 5/27/05.
Sato H, Miura Y, Saito N, Kobayashi K, Takai O. Micropatterned saccharide display on the silicon surface. 2005. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.
Sato, Hajime ; Miura, Yoshiko ; Saito, Nagahiro ; Kobayashi, Kazukiyo ; Takai, Osamu. / Micropatterned saccharide display on the silicon surface. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.1 p.
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