Micropore channell-based simultaneous electrical and optical sensing from single biomolecules, single exosomes to single cells

Hirotoshi Yasaki, Takao Yasui, Sakon Rahong, Takeshi Yanagida, Noritada Kaji, Masaki Kanai, Kazuki Nagashima, Tomoji Kawai, Yoshinobu Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

We realized simultaneous measurements of ionic current and fluorescent imaging in microscale devices towards wide variety analysis of biomolecules, exosomes (<200 nm), circulating tumor cells (<20 μm), and white blood cells (<30 μm). The detection system based on ionic current would distinguish object sizes ranging from 500 nm to 3 μm diameter and fluorescence imaging enabled to detect target objects based on the optical properties. This electrical/optical approach might provide a new sensing scheme to analyze single biomolecules, single exosomes, and single cells with various sizes, shapes, and characteristics.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages2161-2163
Number of pages3
ISBN (Electronic)9780979806476
Publication statusPublished - 2014
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/1410/30/14

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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    Yasaki, H., Yasui, T., Rahong, S., Yanagida, T., Kaji, N., Kanai, M., Nagashima, K., Kawai, T., & Baba, Y. (2014). Micropore channell-based simultaneous electrical and optical sensing from single biomolecules, single exosomes to single cells. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 2161-2163). Chemical and Biological Microsystems Society.