Microscopic ovarian metastasis of the uterine cervical cancer

Naoyuki Toki, Naoki Tsukamoto, Tsunehisa Kaku, Nobuhiro Toh, Toshiaki Saito, Toshiharu Kamura, Keita Matsukuma, Hitoo Nakano

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Abstract

Six hundred forty-seven cases of carcinoma of the uterine cervix with FIGO stages Ib or more were initially treated with hysterectomy at Kyushu University Hospital from 1973 to 1987. In these, 597 cases could be pathologically reviewed for ovarian metastasis. In these 597 cases, 335 were stage Ib, 71 IIa, 185 IIb, and 6 IIIb. Only 3 (0.5%) of 597 showed ovarian metastasis. All 3 cases were stage IIb. None of stage Ib cancer cases had ovarian metastasis. One (0.19%) of 524 squamous cell carcinomas metastasized to the ovary, whereas 2 (5.5%) of 36 pure adenocarcinomas revealed ovarian metastasis. Interestingly, all ovarian metastatic lesions were microscopic in size and found in the ovarian hilus. As for the primary lesion, all cases with ovarian metastasis showed deep myometrial invasion, corpus invasion, and lymphatic permeation. Two cases showed pelvic lymph node metastases and positive peritoneal washing cytology. From the results of our study, it can be said that it is fairly safe to preserve the ovary at the time of radical operation in squamous cell carcinoma of the uterine cervix, but it may not be safe to preserve the ovary in pure adenocarcinoma of the uterine cervix.

Original languageEnglish
Pages (from-to)46-51
Number of pages6
JournalGynecologic Oncology
Volume41
Issue number1
DOIs
Publication statusPublished - Jan 1 1991

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Uterine Cervical Neoplasms
Neoplasm Metastasis
Cervix Uteri
Ovary
Squamous Cell Carcinoma
Adenocarcinoma
Hysterectomy
Cell Biology
Lymph Nodes
Carcinoma
Neoplasms

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Cite this

Toki, N., Tsukamoto, N., Kaku, T., Toh, N., Saito, T., Kamura, T., ... Nakano, H. (1991). Microscopic ovarian metastasis of the uterine cervical cancer. Gynecologic Oncology, 41(1), 46-51. https://doi.org/10.1016/0090-8258(91)90253-2

Microscopic ovarian metastasis of the uterine cervical cancer. / Toki, Naoyuki; Tsukamoto, Naoki; Kaku, Tsunehisa; Toh, Nobuhiro; Saito, Toshiaki; Kamura, Toshiharu; Matsukuma, Keita; Nakano, Hitoo.

In: Gynecologic Oncology, Vol. 41, No. 1, 01.01.1991, p. 46-51.

Research output: Contribution to journalArticle

Toki, N, Tsukamoto, N, Kaku, T, Toh, N, Saito, T, Kamura, T, Matsukuma, K & Nakano, H 1991, 'Microscopic ovarian metastasis of the uterine cervical cancer', Gynecologic Oncology, vol. 41, no. 1, pp. 46-51. https://doi.org/10.1016/0090-8258(91)90253-2
Toki N, Tsukamoto N, Kaku T, Toh N, Saito T, Kamura T et al. Microscopic ovarian metastasis of the uterine cervical cancer. Gynecologic Oncology. 1991 Jan 1;41(1):46-51. https://doi.org/10.1016/0090-8258(91)90253-2
Toki, Naoyuki ; Tsukamoto, Naoki ; Kaku, Tsunehisa ; Toh, Nobuhiro ; Saito, Toshiaki ; Kamura, Toshiharu ; Matsukuma, Keita ; Nakano, Hitoo. / Microscopic ovarian metastasis of the uterine cervical cancer. In: Gynecologic Oncology. 1991 ; Vol. 41, No. 1. pp. 46-51.
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