MICROWELL ARRAY DEVICES FOR PHOSPHOLIPIDS IMAGING IN SINGLE CELLS BY SCANNING PROBE ELECTROSPRAY IONIZATION MASS SPECTROMETRY

Toshihiro Ito, Toyohiro Naito, Hikari Terada, Yoichi Otsuka, Niko Kimura, Noritada Kaji

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, we have developed microwell array devices for phospholipids imaging by scanning probe electrospray ionization mass spectrometry (SPESI-MS) at a single cell level. With a combination of the microwell array devices for single-cell isolation and collection and SPESI-MS, we successfully obtained phospholipids mass information from the surface of a single cell with high spatial resolution. The devices have a great potential as a new platform for single-cell mass spectrometry imaging.

Original languageEnglish
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages593-594
Number of pages2
ISBN (Electronic)9781733419031
Publication statusPublished - 2021
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: Oct 10 2021Oct 14 2021

Publication series

NameMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period10/10/2110/14/21

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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