Mineral balance and bone histology in spontaneously hypertensive rats

Mitsuhiro Furuse, Misao Okumura, Tohru Watanabe, Jun Ichi Okumura

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

SHRs (9 weeks old) were fed diets with or without extra NaCl (2%) and were given water or saline (1%) for 7 weeks. Food and liquid intakes were measured weekly. Blood pressure was determined at 9, 11, 13, 15, and 16 weeks of age. The values for body weight gain and food intake were not influenced by any treatment. Liquid intake greatly increased with the surplus of dietary NaCl. The blood pressure increased with age in all treatments. The increase in blood pressure was enhanced by the addition of NaCl to diet and water. Urinary potassium and calcium excretions were enhanced by added dietary NaCl and saline. Calcium content in the femoral bone was not changed by any treatment, although the number of osteoclast and the area of bone marrow were increased by saline supplementation.

Original languageEnglish
Pages (from-to)731-736
Number of pages6
JournalPhysiology and Behavior
Volume52
Issue number4
DOIs
Publication statusPublished - Jan 1 1992
Externally publishedYes

Fingerprint

Inbred SHR Rats
Minerals
Histology
Blood Pressure
Bone and Bones
Eating
Diet
Calcium
Osteoclasts
Thigh
Weight Gain
Potassium
Therapeutics
Bone Marrow
Body Weight
Water

All Science Journal Classification (ASJC) codes

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Cite this

Mineral balance and bone histology in spontaneously hypertensive rats. / Furuse, Mitsuhiro; Okumura, Misao; Watanabe, Tohru; Okumura, Jun Ichi.

In: Physiology and Behavior, Vol. 52, No. 4, 01.01.1992, p. 731-736.

Research output: Contribution to journalArticle

Furuse, Mitsuhiro ; Okumura, Misao ; Watanabe, Tohru ; Okumura, Jun Ichi. / Mineral balance and bone histology in spontaneously hypertensive rats. In: Physiology and Behavior. 1992 ; Vol. 52, No. 4. pp. 731-736.
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