Mixed functional microarchitectures for orientation selectivity in the mouse primary visual cortex

Satoru Kondo, Takashi Yoshida, Kenichi Ohki

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A minicolumn is the smallest anatomical module in the cortical architecture, but it is still in debate whether it serves as functional units for cortical processing. In the rodent primary visual cortex (V1), neurons with different preferred orientations are mixed horizontally in a salt and pepper manner, but vertical functional organization was not examined. In this study, we found that neurons with similar orientation preference are weakly but significantly clustered vertically in a short length and horizontally in the scale of a minicolumn. Interestingly, the vertical clustering is found only in a part of minicolumns, and others are composed of neurons with a variety of orientation preferences. Thus, the mouse V1 is a mixture of vertical clusters of neurons with various degrees of orientation similarity, which may be the compromise between the brain size and keeping the vertical clusters of similarly tuned neurons at least in a subset of clusters.

Original languageEnglish
Article number13210
JournalNature communications
Volume7
DOIs
Publication statusPublished - Oct 21 2016

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cortexes
Visual Cortex
neurons
Neurons
mice
selectivity
peppers
rodents
set theory
brain
Cluster Analysis
Rodentia
Brain
Salts
modules
salts
Processing

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

Cite this

Mixed functional microarchitectures for orientation selectivity in the mouse primary visual cortex. / Kondo, Satoru; Yoshida, Takashi; Ohki, Kenichi.

In: Nature communications, Vol. 7, 13210, 21.10.2016.

Research output: Contribution to journalArticle

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