Modification of the microchannel in polymer microchips

Yukihiro Okamoto; Yeon Su Park; Noritada Kaji; Manabu Tokeshi; Yoshinobu Baba

Modification of the microchannel in polymer microchips

Yukihiro Okamoto, Yeon Su Park, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

Research output: Contribution to conference › Paper › peer-review

Abstract

We have developed an easy and versatile method for the surface modification of the microchannels in polymer microchips. Our method employed N-5-azido-2- nitrobenzoyloxysuccinimide, a photo-reactive azide, for the surface modification. Unlike the previously developed methods, it allows us to immobilize biomolecules without sacrificing their activity as well as to coat polymers which inhibit protein adsorption. Moreover, it does not require specific equipment, highly toxic chemicals, or labor-intensive procedures.

Original language	English
Pages	892-894
Number of pages	3
Publication status	Published - 2008
Externally published	Yes
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: Oct 12 2008 → Oct 16 2008

Other

Other	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	10/12/08 → 10/16/08

All Science Journal Classification (ASJC) codes

Chemical Engineering (miscellaneous)
Bioengineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Modification of the microchannel in polymer microchips",

abstract = "We have developed an easy and versatile method for the surface modification of the microchannels in polymer microchips. Our method employed N-5-azido-2- nitrobenzoyloxysuccinimide, a photo-reactive azide, for the surface modification. Unlike the previously developed methods, it allows us to immobilize biomolecules without sacrificing their activity as well as to coat polymers which inhibit protein adsorption. Moreover, it does not require specific equipment, highly toxic chemicals, or labor-intensive procedures.",

author = "Yukihiro Okamoto and Park, {Yeon Su} and Noritada Kaji and Manabu Tokeshi and Yoshinobu Baba",

year = "2008",

language = "English",

pages = "892--894",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

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TY - CONF

T1 - Modification of the microchannel in polymer microchips

AU - Okamoto, Yukihiro

AU - Park, Yeon Su

AU - Kaji, Noritada

AU - Tokeshi, Manabu

AU - Baba, Yoshinobu

PY - 2008

Y1 - 2008

N2 - We have developed an easy and versatile method for the surface modification of the microchannels in polymer microchips. Our method employed N-5-azido-2- nitrobenzoyloxysuccinimide, a photo-reactive azide, for the surface modification. Unlike the previously developed methods, it allows us to immobilize biomolecules without sacrificing their activity as well as to coat polymers which inhibit protein adsorption. Moreover, it does not require specific equipment, highly toxic chemicals, or labor-intensive procedures.

AB - We have developed an easy and versatile method for the surface modification of the microchannels in polymer microchips. Our method employed N-5-azido-2- nitrobenzoyloxysuccinimide, a photo-reactive azide, for the surface modification. Unlike the previously developed methods, it allows us to immobilize biomolecules without sacrificing their activity as well as to coat polymers which inhibit protein adsorption. Moreover, it does not require specific equipment, highly toxic chemicals, or labor-intensive procedures.

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UR - http://www.scopus.com/inward/citedby.url?scp=84902436184&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:84902436184

SP - 892

EP - 894

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Modification of the microchannel in polymer microchips

Abstract

Other

All Science Journal Classification (ASJC) codes

UN SDGs

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