TY - GEN
T1 - Modulation and transmission of sweet taste information for energy homeostasis
AU - Sanematsu, Keisuke
AU - Horio, Nao
AU - Murata, Yoshihiro
AU - Yoshida, Ryusuke
AU - Ohkuri, Tadahiro
AU - Shigemura, Noriatsu
AU - Ninomiya, Yuzo
PY - 2009/7
Y1 - 2009/7
N2 - Perception of sweet taste is important for animals to detect external energy source of calories. In mice, sweet-sensitive cells possess a leptin receptor. Increase of plasma leptin with increasing internal energy storage in the adipose tissue suppresses sweet taste responses via this receptor. Data from our recent studies indicate that leptin may also modulate sweet taste sensation in humans with a diurnal variation in sweet sensitivity. This leptin modulation of sweet taste information to the brain may influence individuals' preference and ingestive behavior, thereby playing important roles in regulation of energy homeostasis.
AB - Perception of sweet taste is important for animals to detect external energy source of calories. In mice, sweet-sensitive cells possess a leptin receptor. Increase of plasma leptin with increasing internal energy storage in the adipose tissue suppresses sweet taste responses via this receptor. Data from our recent studies indicate that leptin may also modulate sweet taste sensation in humans with a diurnal variation in sweet sensitivity. This leptin modulation of sweet taste information to the brain may influence individuals' preference and ingestive behavior, thereby playing important roles in regulation of energy homeostasis.
UR - http://www.scopus.com/inward/record.url?scp=68649086671&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=68649086671&partnerID=8YFLogxK
U2 - 10.1111/j.1749-6632.2009.03893.x
DO - 10.1111/j.1749-6632.2009.03893.x
M3 - Conference contribution
C2 - 19686118
AN - SCOPUS:68649086671
SN - 9781573317382
T3 - Annals of the New York Academy of Sciences
SP - 102
EP - 106
BT - International Symposium on Olfaction and Taste
PB - Blackwell Publishing Inc.
ER -