Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation

Katsuya Ogata, Takao Yamasaki, Shozo Tobimatsu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Transcranial direct current stimulation (tDCS) can modulate cortical function transiently. This effect is monitored by motor evoked potentials (MEPs). The excitability of intracortical circuits in the motor cortex is assessed by paired pulse stimulation. In previous MEP studies, the modulation of short latency intracortical inhibition (SICI) and intracortical facilitation (ICF) with tDCS was demonstrated. In order to elucidate the neural mechanisms of tDCS, we evaluated the long latency intracortical inhibition (LICI) and short latency afferent inhibition (SAI) as well as SICI and ICF as objective parameters. There was a siginificant modulation of MEP amplitudes of single pulse TMS, however, SICI, ICF, LICI, and SAI were not significantly altered. Our results suggest that tDCS does not modulate neurotransmitter related to each parameter. Therefore, the modulation of MEP amplitudes of single pulse TMS may result from the change of membrane potentials.

Original languageEnglish
Title of host publication2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
Pages2000-2003
Number of pages4
DOIs
Publication statusPublished - 2007
Event2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 - Beijing, China
Duration: May 23 2007May 27 2007

Other

Other2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
CountryChina
CityBeijing
Period5/23/075/27/07

Fingerprint

Motor Cortex
Bioelectric potentials
Modulation
Motor Evoked Potentials
Transcranial Direct Current Stimulation
Inhibition (Psychology)
Membrane Potentials
Membranes
Neurotransmitter Agents
Networks (circuits)

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Medicine(all)

Cite this

Ogata, K., Yamasaki, T., & Tobimatsu, S. (2007). Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation. In 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 (pp. 2000-2003). [4382099] https://doi.org/10.1109/ICCME.2007.4382099

Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation. / Ogata, Katsuya; Yamasaki, Takao; Tobimatsu, Shozo.

2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007. 2007. p. 2000-2003 4382099.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ogata, K, Yamasaki, T & Tobimatsu, S 2007, Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation. in 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007., 4382099, pp. 2000-2003, 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007, Beijing, China, 5/23/07. https://doi.org/10.1109/ICCME.2007.4382099
Ogata K, Yamasaki T, Tobimatsu S. Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation. In 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007. 2007. p. 2000-2003. 4382099 https://doi.org/10.1109/ICCME.2007.4382099
Ogata, Katsuya ; Yamasaki, Takao ; Tobimatsu, Shozo. / Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation. 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007. 2007. pp. 2000-2003
@inproceedings{a36f2a578d7446ba9cab0273d845ee62,
title = "Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation",
abstract = "Transcranial direct current stimulation (tDCS) can modulate cortical function transiently. This effect is monitored by motor evoked potentials (MEPs). The excitability of intracortical circuits in the motor cortex is assessed by paired pulse stimulation. In previous MEP studies, the modulation of short latency intracortical inhibition (SICI) and intracortical facilitation (ICF) with tDCS was demonstrated. In order to elucidate the neural mechanisms of tDCS, we evaluated the long latency intracortical inhibition (LICI) and short latency afferent inhibition (SAI) as well as SICI and ICF as objective parameters. There was a siginificant modulation of MEP amplitudes of single pulse TMS, however, SICI, ICF, LICI, and SAI were not significantly altered. Our results suggest that tDCS does not modulate neurotransmitter related to each parameter. Therefore, the modulation of MEP amplitudes of single pulse TMS may result from the change of membrane potentials.",
author = "Katsuya Ogata and Takao Yamasaki and Shozo Tobimatsu",
year = "2007",
doi = "10.1109/ICCME.2007.4382099",
language = "English",
isbn = "1424410789",
pages = "2000--2003",
booktitle = "2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007",

}

TY - GEN

T1 - Modulation of intracortical inhibition and facilitation of motor cortex through transcranial direct current stimulation

AU - Ogata, Katsuya

AU - Yamasaki, Takao

AU - Tobimatsu, Shozo

PY - 2007

Y1 - 2007

N2 - Transcranial direct current stimulation (tDCS) can modulate cortical function transiently. This effect is monitored by motor evoked potentials (MEPs). The excitability of intracortical circuits in the motor cortex is assessed by paired pulse stimulation. In previous MEP studies, the modulation of short latency intracortical inhibition (SICI) and intracortical facilitation (ICF) with tDCS was demonstrated. In order to elucidate the neural mechanisms of tDCS, we evaluated the long latency intracortical inhibition (LICI) and short latency afferent inhibition (SAI) as well as SICI and ICF as objective parameters. There was a siginificant modulation of MEP amplitudes of single pulse TMS, however, SICI, ICF, LICI, and SAI were not significantly altered. Our results suggest that tDCS does not modulate neurotransmitter related to each parameter. Therefore, the modulation of MEP amplitudes of single pulse TMS may result from the change of membrane potentials.

AB - Transcranial direct current stimulation (tDCS) can modulate cortical function transiently. This effect is monitored by motor evoked potentials (MEPs). The excitability of intracortical circuits in the motor cortex is assessed by paired pulse stimulation. In previous MEP studies, the modulation of short latency intracortical inhibition (SICI) and intracortical facilitation (ICF) with tDCS was demonstrated. In order to elucidate the neural mechanisms of tDCS, we evaluated the long latency intracortical inhibition (LICI) and short latency afferent inhibition (SAI) as well as SICI and ICF as objective parameters. There was a siginificant modulation of MEP amplitudes of single pulse TMS, however, SICI, ICF, LICI, and SAI were not significantly altered. Our results suggest that tDCS does not modulate neurotransmitter related to each parameter. Therefore, the modulation of MEP amplitudes of single pulse TMS may result from the change of membrane potentials.

UR - http://www.scopus.com/inward/record.url?scp=48149107838&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48149107838&partnerID=8YFLogxK

U2 - 10.1109/ICCME.2007.4382099

DO - 10.1109/ICCME.2007.4382099

M3 - Conference contribution

SN - 1424410789

SN - 9781424410781

SP - 2000

EP - 2003

BT - 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

ER -