Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions

Seiji Shinkai, Masayuki Takeuchi

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.

Original languageEnglish
Pages (from-to)1250-1259
Number of pages10
JournalBiosensors and Bioelectronics
Volume20
Issue number6
DOIs
Publication statusPublished - Dec 15 2004

Fingerprint

Molecular Imprinting
Artificial Receptors
Boronic Acids
Sugars
Fluorescence
Acids

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry

Cite this

Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions. / Shinkai, Seiji; Takeuchi, Masayuki.

In: Biosensors and Bioelectronics, Vol. 20, No. 6, 15.12.2004, p. 1250-1259.

Research output: Contribution to journalArticle

Shinkai, Seiji ; Takeuchi, Masayuki. / Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions. In: Biosensors and Bioelectronics. 2004 ; Vol. 20, No. 6. pp. 1250-1259.
@article{4287c48776bf45199d3245cf03225bab,
title = "Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions",
abstract = "Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.",
author = "Seiji Shinkai and Masayuki Takeuchi",
year = "2004",
month = "12",
day = "15",
doi = "10.1016/j.bios.2004.03.036",
language = "English",
volume = "20",
pages = "1250--1259",
journal = "Biosensors",
issn = "0956-5663",
publisher = "Multidisciplinary Digital Publishing Institute",
number = "6",

}

TY - JOUR

T1 - Molecular design of synthetic receptors with dynamic, imprinting, and allosteric functions

AU - Shinkai, Seiji

AU - Takeuchi, Masayuki

PY - 2004/12/15

Y1 - 2004/12/15

N2 - Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.

AB - Sugar recognition in an aqueous system has been achieved using a boronic acid-diol interaction. Combination with an intramolecular amino group has enabled us to read out the binding process as a change in the fluorescence intensity. The novel interaction has been extended to dynamic sugar sensing utilizing an allosteric effect, molecular imprinting, and control of molecular assemblies.

UR - http://www.scopus.com/inward/record.url?scp=8844280085&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=8844280085&partnerID=8YFLogxK

U2 - 10.1016/j.bios.2004.03.036

DO - 10.1016/j.bios.2004.03.036

M3 - Article

C2 - 15556374

AN - SCOPUS:8844280085

VL - 20

SP - 1250

EP - 1259

JO - Biosensors

JF - Biosensors

SN - 0956-5663

IS - 6

ER -