Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study

V. Meenakumari, A. Milton Franklin Benial, Kazuhiro Ichikawa, Ken-Ichi Yamada, A. Jawahar, Hideo Utsumi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of 14N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T2e) decreases with increasing concentration. The isotropic g-values were obtained.

Original languageEnglish
Title of host publicationSolid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012
Pages952-953
Number of pages2
DOIs
Publication statusPublished - Mar 15 2013
Event57th DAE Solid State Physics Symposium 2012 - Bombay, Mumbai, India
Duration: Dec 3 2012Dec 7 2012

Publication series

NameAIP Conference Proceedings
Volume1512
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other57th DAE Solid State Physics Symposium 2012
CountryIndia
CityBombay, Mumbai
Period12/3/1212/7/12

Fingerprint

magnetic resonance
electron paramagnetic resonance
molecular dynamics
augmentation
free radicals
line shape
proportion
relaxation time
water

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Plant Science
  • Physics and Astronomy(all)
  • Nature and Landscape Conservation

Cite this

Meenakumari, V., Benial, A. M. F., Ichikawa, K., Yamada, K-I., Jawahar, A., & Utsumi, H. (2013). Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study. In Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012 (pp. 952-953). (AIP Conference Proceedings; Vol. 1512). https://doi.org/10.1063/1.4791356

Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI) : An ESR study. / Meenakumari, V.; Benial, A. Milton Franklin; Ichikawa, Kazuhiro; Yamada, Ken-Ichi; Jawahar, A.; Utsumi, Hideo.

Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012. 2013. p. 952-953 (AIP Conference Proceedings; Vol. 1512).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Meenakumari, V, Benial, AMF, Ichikawa, K, Yamada, K-I, Jawahar, A & Utsumi, H 2013, Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study. in Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012. AIP Conference Proceedings, vol. 1512, pp. 952-953, 57th DAE Solid State Physics Symposium 2012, Bombay, Mumbai, India, 12/3/12. https://doi.org/10.1063/1.4791356
Meenakumari V, Benial AMF, Ichikawa K, Yamada K-I, Jawahar A, Utsumi H. Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study. In Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012. 2013. p. 952-953. (AIP Conference Proceedings). https://doi.org/10.1063/1.4791356
Meenakumari, V. ; Benial, A. Milton Franklin ; Ichikawa, Kazuhiro ; Yamada, Ken-Ichi ; Jawahar, A. ; Utsumi, Hideo. / Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI) : An ESR study. Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012. 2013. pp. 952-953 (AIP Conference Proceedings).
@inproceedings{aa7eee4e7da5454db6ececec54f7db79,
title = "Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI): An ESR study",
abstract = "Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of 14N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T2e) decreases with increasing concentration. The isotropic g-values were obtained.",
author = "V. Meenakumari and Benial, {A. Milton Franklin} and Kazuhiro Ichikawa and Ken-Ichi Yamada and A. Jawahar and Hideo Utsumi",
year = "2013",
month = "3",
day = "15",
doi = "10.1063/1.4791356",
language = "English",
isbn = "9780735411333",
series = "AIP Conference Proceedings",
pages = "952--953",
booktitle = "Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012",

}

TY - GEN

T1 - Molecular dynamics dependence of overhauser-enhanced magnetic resonance imaging (OMRI)

T2 - An ESR study

AU - Meenakumari, V.

AU - Benial, A. Milton Franklin

AU - Ichikawa, Kazuhiro

AU - Yamada, Ken-Ichi

AU - Jawahar, A.

AU - Utsumi, Hideo

PY - 2013/3/15

Y1 - 2013/3/15

N2 - Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of 14N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T2e) decreases with increasing concentration. The isotropic g-values were obtained.

AB - Electron spin resonance (ESR) and Overhauser-enhanced magnetic resonance imaging (OMRI) studies were carried out for various concentrations of 14N-labeled 3-carbamoyl-2,2,5,5-tetramethyl-pyrrolidin-1-yloxy (carbamoyl-PROXYL) in pure water. The ESR parameters and Overhauser enhancement factor were estimated. Line width and line shape analysis confirm that the lines broaden in proportion to agent concentration and are approximately Lorentzian. The contribution of Lorentzian component and Overhauser enhancement factor (OEF) attain maximum in the range of 2.5-3 mM concentration. The agent concentration was optimized as 2.5-3 mM for free radical imaging. The observed spin-spin relaxation time (T2e) decreases with increasing concentration. The isotropic g-values were obtained.

UR - http://www.scopus.com/inward/record.url?scp=84874895069&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874895069&partnerID=8YFLogxK

U2 - 10.1063/1.4791356

DO - 10.1063/1.4791356

M3 - Conference contribution

AN - SCOPUS:84874895069

SN - 9780735411333

T3 - AIP Conference Proceedings

SP - 952

EP - 953

BT - Solid State Physics - Proceedings of the 57th DAE Solid State Physics Symposium 2012

ER -