TY - JOUR
T1 - Molecular dynamics simulation of fluorination effect for solvation of trifluoromethylbenzoic acid isomers in supercritical carbon dioxide
AU - Higashi, H.
AU - Iwai, Y.
AU - Miyazaki, K.
AU - Arai, Y.
N1 - Funding Information:
The present study was supported in part by a Grant-in-Aid for the 21st century center of excellent (COE) program, “Functional Innovation of Molecular Informatics”, from the Ministry of Education, Science, Sports and Culture of Japan and a grant provided by NEDO (via JCII) based on the project “Res. & Dev. of Environmentally Friendly Tech. Using SCF” of Ind. Sci. Tech. Frontier Program (METI).
PY - 2005/8/30
Y1 - 2005/8/30
N2 - A molecular dynamics (MD) simulation was applied to carbon dioxide + trifluoromethylbenzoic acid isomer and carbon dioxide + methylbenzoic acid isomer systems to investigate the interactions between carbon dioxide and the solutes. The pair correlation functions between the carbon dioxide and trifluoromethyl group or methyl group in the solutes were calculated to study the fluorination effect of solvation. As a result, it was found that the interactions between carbon dioxide and trifluoromethyl group in trifluoromethylbenzoic acid isomers were stronger than those between carbon dioxide and the methyl group in methylbenzoic acid isomers. The simulation results had the same tendency as the experimental solubility enhancements and coincided with the trend of the interaction parameters of the Peng-Robinson equation of state that were determined from the solubility data.
AB - A molecular dynamics (MD) simulation was applied to carbon dioxide + trifluoromethylbenzoic acid isomer and carbon dioxide + methylbenzoic acid isomer systems to investigate the interactions between carbon dioxide and the solutes. The pair correlation functions between the carbon dioxide and trifluoromethyl group or methyl group in the solutes were calculated to study the fluorination effect of solvation. As a result, it was found that the interactions between carbon dioxide and trifluoromethyl group in trifluoromethylbenzoic acid isomers were stronger than those between carbon dioxide and the methyl group in methylbenzoic acid isomers. The simulation results had the same tendency as the experimental solubility enhancements and coincided with the trend of the interaction parameters of the Peng-Robinson equation of state that were determined from the solubility data.
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U2 - 10.1080/08927020500183299
DO - 10.1080/08927020500183299
M3 - Article
AN - SCOPUS:24644518478
SN - 0892-7022
VL - 31
SP - 725
EP - 730
JO - Molecular Simulation
JF - Molecular Simulation
IS - 10
ER -