Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam

Hiroki Takakuwa, Tetsu Yamashiro, Mai Q. Le, Lien S. Phuong, Hiroichi Ozaki, Ryota Tsunekuni, Tatsufumi Usui, Hiroshi Ito, Masami Morimatsu, Yukiko Tomioka, Tsuyoshi Yamaguchi, Toshihiro Ito, Toshiyuki Murase, Etsuro Ono, Koichi Otsuki

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Repeated epizootics of highly pathogenic avian influenza (HPAI) virus subtype H5N1 were reported from 2003 to 2005 among poultry in Vietnam. More than 200 million birds were killed to control the spread of the disease. Human cases of H5N1 infection have been sporadically reported in an area where repeated H5N1 outbreaks among birds had occurred. Subtype H5N1 strains are established as endemic among poultry in Vietnam, however, insights into how avian influenza viruses including the H5N1 subtype are maintained in endemic areas is not clear. In order to determine the prevalence of different avian influenza viruses (AIVs), including H5N1 circulating among poultry in northern Vietnam, surveillance was conducted during the years 2006-2009. A subtype H5N1 strain was isolated from an apparently healthy duck reared on a farm in northern Vietnam in 2008 and was identified as an HPAI. Although only one H5N1 virus was isolated, it supports the view that healthy domestic ducks play a pivotal role in maintaining and transmitting H5N1 viruses which cause disease outbreaks in northern Vietnam. In addition, a total of 26 AIVs with low pathogenicity were isolated from poultry and phylogenetic analysis of all the eight gene segments revealed their diverse genetical backgrounds, implying that reassortments have occurred frequently among strains in northern Vietnam. It is, therefore, important to monitor the prevalence of influenza viruses among healthy poultry between epidemics in an area where AIVs are endemic.

Original languageEnglish
Pages (from-to)192-200
Number of pages9
JournalPreventive Veterinary Medicine
Volume103
Issue number2-3
DOIs
Publication statusPublished - Feb 1 2012

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molecular epidemiology
Influenza in Birds
Molecular Epidemiology
Vietnam
Poultry
Orthomyxoviridae
Influenza A virus
flocks
poultry
farms
H5N1 Subtype Influenza A Virus
Ducks
Birds
Disease Outbreaks
ducks
monitoring
birds
avian influenza
Virulence
Farms

All Science Journal Classification (ASJC) codes

  • Food Animals
  • Animal Science and Zoology

Cite this

Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam. / Takakuwa, Hiroki; Yamashiro, Tetsu; Le, Mai Q.; Phuong, Lien S.; Ozaki, Hiroichi; Tsunekuni, Ryota; Usui, Tatsufumi; Ito, Hiroshi; Morimatsu, Masami; Tomioka, Yukiko; Yamaguchi, Tsuyoshi; Ito, Toshihiro; Murase, Toshiyuki; Ono, Etsuro; Otsuki, Koichi.

In: Preventive Veterinary Medicine, Vol. 103, No. 2-3, 01.02.2012, p. 192-200.

Research output: Contribution to journalArticle

Takakuwa, H, Yamashiro, T, Le, MQ, Phuong, LS, Ozaki, H, Tsunekuni, R, Usui, T, Ito, H, Morimatsu, M, Tomioka, Y, Yamaguchi, T, Ito, T, Murase, T, Ono, E & Otsuki, K 2012, 'Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam', Preventive Veterinary Medicine, vol. 103, no. 2-3, pp. 192-200. https://doi.org/10.1016/j.prevetmed.2011.09.014
Takakuwa, Hiroki ; Yamashiro, Tetsu ; Le, Mai Q. ; Phuong, Lien S. ; Ozaki, Hiroichi ; Tsunekuni, Ryota ; Usui, Tatsufumi ; Ito, Hiroshi ; Morimatsu, Masami ; Tomioka, Yukiko ; Yamaguchi, Tsuyoshi ; Ito, Toshihiro ; Murase, Toshiyuki ; Ono, Etsuro ; Otsuki, Koichi. / Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam. In: Preventive Veterinary Medicine. 2012 ; Vol. 103, No. 2-3. pp. 192-200.
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