Molecular evolution of the Amy multigenes in the subgenus Sophophora of Drosophila

Nobuyuki Inomata, Hidenori Tachida, Tsuneyuki Yamazaki

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Molecular evolution of the Amy multigenes in Drosophila was investigated using PCR amplification. Twenty-five partial Amy sequences from 13 species belonging mainly to the subgenus Sophophora were determined, and a molecular phylogeny of the Amy genes in Drosophila was constructed, together with published Amy sequences. Clusterings of species are mostly consistent with the traditional classification and that inferred from other genes. From sequence divergence between PCR products, several species, including D. elegans and D. fuyamai, were suggested to have multiple copies of the Amy genes. The loss of an intron took place at least three times after the Sophophora radiation. In order to investigate the mechanism of sequence evolution, the numbers of amino acid replacement and synonymous substitutions in five lineages were estimated. The heterogeneity in the relative numbers of synonymous and replacement substitutions among the lineages was found. Possible roles of selection in the sequence evolution of the Amy gene are discussed.

Original languageEnglish
Pages (from-to)942-950
Number of pages9
JournalMolecular Biology and Evolution
Volume14
Issue number9
DOIs
Publication statusPublished - Jan 1 1997

Fingerprint

Molecular Evolution
Drosophila
gene
Genes
substitution
genes
replacement
Polymerase Chain Reaction
Phylogeny
Introns
Cluster Analysis
introns
amplification
phylogeny
amino acid
divergence
Radiation
taxonomy
Amino Acids
amino acids

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

Cite this

Molecular evolution of the Amy multigenes in the subgenus Sophophora of Drosophila. / Inomata, Nobuyuki; Tachida, Hidenori; Yamazaki, Tsuneyuki.

In: Molecular Biology and Evolution, Vol. 14, No. 9, 01.01.1997, p. 942-950.

Research output: Contribution to journalArticle

Inomata, Nobuyuki ; Tachida, Hidenori ; Yamazaki, Tsuneyuki. / Molecular evolution of the Amy multigenes in the subgenus Sophophora of Drosophila. In: Molecular Biology and Evolution. 1997 ; Vol. 14, No. 9. pp. 942-950.
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