Molecular mechanisms of the antiatherogenic action of adiponectin

Kunihisa Kobayashi, Toyoshi Inoguchi

    Research output: Contribution to journalReview articlepeer-review

    1 Citation (Scopus)


    Recently, many investigators have reported that adipocytes secrete a variety of bioactive substances, termed adipokines (adipocytokines), including tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), leptin, resistin, adiponectin and so on. Adiponectin is most abundant in the plasma and produced exclusively by adipocytes. This adipokine has been reported to be an exciting player in the field of energy homeostasis regulation. Furthermore, adiponectin has been shown to have antiatherogenic properties in epidemiological, in vitro and in vivo studies. This review summarizes the currently available information regarding this important biomolecule and discusses its feasibility for the treatment of atherosclerotic diseases.

    Original languageEnglish
    Pages (from-to)7-9
    Number of pages3
    JournalVascular Disease Prevention
    Issue number1
    Publication statusPublished - Feb 2007

    All Science Journal Classification (ASJC) codes

    • Epidemiology
    • Cardiology and Cardiovascular Medicine


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