Molecular mechanisms of the antiatherogenic action of adiponectin

Kunihisa Kobayashi; Toyoshi Inoguchi

doi:10.2174/156727007779802714

Molecular mechanisms of the antiatherogenic action of adiponectin

Kunihisa Kobayashi, Toyoshi Inoguchi

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Recently, many investigators have reported that adipocytes secrete a variety of bioactive substances, termed adipokines (adipocytokines), including tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), leptin, resistin, adiponectin and so on. Adiponectin is most abundant in the plasma and produced exclusively by adipocytes. This adipokine has been reported to be an exciting player in the field of energy homeostasis regulation. Furthermore, adiponectin has been shown to have antiatherogenic properties in epidemiological, in vitro and in vivo studies. This review summarizes the currently available information regarding this important biomolecule and discusses its feasibility for the treatment of atherosclerotic diseases.

Original language	English
Pages (from-to)	7-9
Number of pages	3
Journal	Vascular Disease Prevention
Volume	4
Issue number	1
DOIs	https://doi.org/10.2174/156727007779802714
Publication status	Published - Feb 2007

All Science Journal Classification (ASJC) codes

Epidemiology
Cardiology and Cardiovascular Medicine

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abstract = "Recently, many investigators have reported that adipocytes secrete a variety of bioactive substances, termed adipokines (adipocytokines), including tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), leptin, resistin, adiponectin and so on. Adiponectin is most abundant in the plasma and produced exclusively by adipocytes. This adipokine has been reported to be an exciting player in the field of energy homeostasis regulation. Furthermore, adiponectin has been shown to have antiatherogenic properties in epidemiological, in vitro and in vivo studies. This review summarizes the currently available information regarding this important biomolecule and discusses its feasibility for the treatment of atherosclerotic diseases.",

author = "Kunihisa Kobayashi and Toyoshi Inoguchi",

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Molecular mechanisms of the antiatherogenic action of adiponectin

Abstract

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