TY - JOUR
T1 - Molecular vibrational imaging of a human cell by multiplex coherent anti-Stokes Raman scattering microspectroscopy using a supercontinuum light source
AU - Kano, Hideaki
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2008/11
Y1 - 2008/11
N2 - Molecular vibrational images of human cells are obtained by multiplex coherent anti-Stokes Raman scattering (CARS) microspectroscopy. The CARS images of HeLa cells at the C-H stretching vibrational mode clearly show various organelles such as nucleolus, chromosome, cell membrane, and nuclear membrane with high vibrational contrast. Filament-like structures are also found to be observed in interphase, while it is not clearly observed in M phase. These structures most probably visualize endoplasmic reticulum (ER) network.
AB - Molecular vibrational images of human cells are obtained by multiplex coherent anti-Stokes Raman scattering (CARS) microspectroscopy. The CARS images of HeLa cells at the C-H stretching vibrational mode clearly show various organelles such as nucleolus, chromosome, cell membrane, and nuclear membrane with high vibrational contrast. Filament-like structures are also found to be observed in interphase, while it is not clearly observed in M phase. These structures most probably visualize endoplasmic reticulum (ER) network.
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U2 - 10.1002/jrs.2041
DO - 10.1002/jrs.2041
M3 - Article
AN - SCOPUS:55449134344
VL - 39
SP - 1649
EP - 1652
JO - Journal of Raman Spectroscopy
JF - Journal of Raman Spectroscopy
SN - 0377-0486
IS - 11
ER -