Abstract
We have successfully achieved the molybdenum hexacarbonyl [Mo(CO) 6] mediated desulfurization of thiols and disulfides. In this reaction, the sulfhydryl (SH) mercapto groups of aryl, benzyl, primary and secondary alkyl thiols, and S-S single bonds of disulfides can be removed. This reaction has high functional group tolerance and is not affected by steric hindrance. The results of the reactions in acetone-d 6 suggest that the sources of hydrogen in the thiol and disulfide desulfurizations are the hydrogen atom(s) of a sulfhydryl group and acetone (solvent), respectively, and that the desulfurization proceeds via the formation of an organomolybdenum species.
| Original language | English |
|---|---|
| Article number | st-2014-u0304-l |
| Pages (from-to) | 1869-1872 |
| Number of pages | 4 |
| Journal | Synlett |
| Volume | 25 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - Aug 2014 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Organic Chemistry
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Wang, Z., Kuninobu, Y., & Kanai, M. (2014). Molybdenum-mediated desulfurization of dhiols and disulfides. Synlett, 25(13), 1869-1872. [st-2014-u0304-l]. https://doi.org/10.1055/s-0034-1378315