Abstract
We have successfully achieved the molybdenum hexacarbonyl [Mo(CO) 6] mediated desulfurization of thiols and disulfides. In this reaction, the sulfhydryl (SH) mercapto groups of aryl, benzyl, primary and secondary alkyl thiols, and S-S single bonds of disulfides can be removed. This reaction has high functional group tolerance and is not affected by steric hindrance. The results of the reactions in acetone-d 6 suggest that the sources of hydrogen in the thiol and disulfide desulfurizations are the hydrogen atom(s) of a sulfhydryl group and acetone (solvent), respectively, and that the desulfurization proceeds via the formation of an organomolybdenum species.
Original language | English |
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Article number | st-2014-u0304-l |
Pages (from-to) | 1869-1872 |
Number of pages | 4 |
Journal | Synlett |
Volume | 25 |
Issue number | 13 |
DOIs | |
Publication status | Published - Aug 2014 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Organic Chemistry