Monoamine oxidase genes polymorphisms and mood disorder

Taro Muramatsu, Sachio Matsushita, Shigenobu Kanba, Susumu Higuchi, Hiroshi Manki, Eiji Suzuki, Masahiro Asai

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Abstract

We investigated a genetic association between mood disorders (bipolar and unipolar) and the alleles of monoamine oxidase (MAO) A and B (MAOA and MAOB). One hundred and twelve unrelated Japanese patients (60 bipolar, 52 unipolar) and 100 controls were genotyped for three markers of MAOA and for one marker of MAOB. No statistically significant difference in the distribution of the alleles existed between cases and controls. Therefore, our results did not support the involvement of the alleles at MAOA and MAOB in the etiology of mood disorder.

Original languageEnglish
Pages (from-to)494-496
Number of pages3
JournalAmerican Journal of Medical Genetics - Neuropsychiatric Genetics
Volume74
Issue number5
DOIs
Publication statusPublished - Oct 15 1997

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All Science Journal Classification (ASJC) codes

  • Genetics(clinical)
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience

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