We investigated a genetic association between mood disorders (bipolar and unipolar) and the alleles of monoamine oxidase (MAO) A and B (MAOA and MAOB). One hundred and twelve unrelated Japanese patients (60 bipolar, 52 unipolar) and 100 controls were genotyped for three markers of MAOA and for one marker of MAOB. No statistically significant difference in the distribution of the alleles existed between cases and controls. Therefore, our results did not support the involvement of the alleles at MAOA and MAOB in the etiology of mood disorder.
|Number of pages||3|
|Journal||American Journal of Medical Genetics - Neuropsychiatric Genetics|
|Publication status||Published - Oct 15 1997|
All Science Journal Classification (ASJC) codes
- Psychiatry and Mental health
- Cellular and Molecular Neuroscience