Morphology of Gastric Microcirculation in Cirrhosis

Makoto Hashizume, Kenzo Tanaka, Kiyoshi Inokuchi

Research output: Contribution to journalArticlepeer-review

136 Citations (Scopus)

Abstract

Morphologic alterations in the gastric microcirculation in cirrhosis were investigated following infusion of a silicone rubber compound into vessels of the excised stomach which was then cleared with methyl salicylate. In cirrhosis, arteriovenous anastomoses 15 to 50 jum in diameter were present in 5 of 10 patients; spiral arterioles were less than one‐tenth as numerous as in stomachs from noncirrhotic patients. The arterioles mainly had a straight pattern and precapillaries, capillaries, and submucosal and subserosal veins were dilated in cirrhotics (p < 0.05). The number of arteriovenous anastomoses was unrelated to the degree of vascular dilatation and the number of spiral arterioles. These morphological alterations are consistent with decreased arteriovenous flow resistance in the stomach of cirrhotic patients.

Original languageEnglish
Pages (from-to)1008-1012
Number of pages5
JournalHepatology
Volume3
Issue number6
DOIs
Publication statusPublished - 1983

All Science Journal Classification (ASJC) codes

  • Hepatology

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