Morphometric deformations of small airways and alveoli under quasi-static inflation process

Toshihiro Sera, Kentaro Uesugi, Naoto Yagi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Localized morphometric deformations of small airways and alveoli during respiration have many biomedical and physiological implications. We developed fast synchrotron radiation CT system to visualize the small airways and alveoli of an intact mouse lung without fixation and dehydration, and analyzed their localized morphometric deformations between functional residual capacity (FRC) and total lung capacity (TLC). In the diameter behavior, the averaged and range values were significantly larger for smaller airways (68.8%, range: 0.36-0.89) than larger airways (45.2%, range: 0.40-0.57). These results indicated that the airway did not deformed in same manner and that these morphological differences characterized the heterogeneous lung function.

Original languageEnglish
Pages (from-to)465-468
Number of pages4
JournalJournal of physiological anthropology and applied human science
Volume24
Issue number4
DOIs
Publication statusPublished - Jul 1 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Social Sciences(all)

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