MPO-ANCA-positive Wegener's granulomatosis presenting with hypertrophic cranial pachymeningitis: Case report and review of the literature

Mitsuteru Akahoshi, Goichi Yoshimoto, Hitoshi Nakashima, Katsuhisa Miyake, Yasushi Inoue, Yosuke Tanaka, Hiroshi Tsukamoto, Takahiko Horiuchi, Takeshi Otsuka, Mine Harada

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Abstract

We describe a case of hypertrophic cranial pachymeningitis (HCP) associated with Wegener's granulomatosis (WG) in a 60-year-old man presenting with chronic headache and multiple cranial nerve neuropathies. A test for antibodies to the neutrophil cytoplasmic protein myeloperoxidase (MPO-ANCA) was positive in this case. We review the literature on perinuclear (p)-ANCA-related HCP, including our case. This case indicates the link between MPO-ANCA-positive WG and HCP.

Original languageEnglish
Pages (from-to)179-183
Number of pages5
JournalModern Rheumatology
Volume14
Issue number2
DOIs
Publication statusPublished - Jun 1 2004

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All Science Journal Classification (ASJC) codes

  • Rheumatology

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