MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions

Tomoko Shiraishi, Toru Chikui, Daisuke Inadomi, Marie Hashimoto, Chika Horio, Toyohiro Kagawa, Kunihiro Miwa, Kenji Yuasa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives To compare magnetic resonance imaging (MRI) findings between patients with malignant lymphoma (ML) and squamous cell carcinoma (SCC) in the head and neck regions, and to show the characteristic findings for ML. Methods We analyzed 10 lesions in nine patients with ML and 25 lesions in 25 patients with SCC. Diffusion-weighted imaging, T1-weighted imaging, and T2-weighted imaging were performed for all lesions. We estimated the apparent diffusion coefficients (ADCs) with b-factors of 0, 500, and 1000 s/mm2, and obtained the means and standard deviations. In 29 cases, dynamic contrast-enhanced MRI (DCE-MRI) was performed and time–intensity curves were obtained. The peak time, maximum-to-initial ratio (MI ratio), end-to-maximum ratio, and end-to-initial ratio (EI ratio) were estimated. Receiver-operating characteristic analyses were performed to estimate the diagnostic power for these indices. Results The mean ADC for ML (0.762 ± 0.126 × 10−3 mm2/s) was significantly lower than that for SCC (1.24 ± 0.22 × 10-3 mm2/s, p < 0.0001). ML had a smaller MI ratio (2.13 ± 0.26) and smaller EI ratio (1.90 ± 0.29) than SCC (MI ratio: 2.46 ± 0.38, p = 0.033; EI ratio: 2.19 ± 0.29, p = 0.025). The area under the curve for the mean ADC (0.989) was higher than those for the MI ratio (0.779) and EI ratio (0.792).

Original languageEnglish
Pages (from-to)98-104
Number of pages7
JournalOral Radiology
Volume32
Issue number2
DOIs
Publication statusPublished - Jul 23 2016

Fingerprint

Lymphoma
Magnetic Resonance Imaging
Squamous Cell Carcinoma
ROC Curve
Area Under Curve
Carcinoma, squamous cell of head and neck

All Science Journal Classification (ASJC) codes

  • Dentistry (miscellaneous)
  • Radiology Nuclear Medicine and imaging

Cite this

MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions. / Shiraishi, Tomoko; Chikui, Toru; Inadomi, Daisuke; Hashimoto, Marie; Horio, Chika; Kagawa, Toyohiro; Miwa, Kunihiro; Yuasa, Kenji.

In: Oral Radiology, Vol. 32, No. 2, 23.07.2016, p. 98-104.

Research output: Contribution to journalArticle

Shiraishi, T, Chikui, T, Inadomi, D, Hashimoto, M, Horio, C, Kagawa, T, Miwa, K & Yuasa, K 2016, 'MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions', Oral Radiology, vol. 32, no. 2, pp. 98-104. https://doi.org/10.1007/s11282-015-0219-3
Shiraishi, Tomoko ; Chikui, Toru ; Inadomi, Daisuke ; Hashimoto, Marie ; Horio, Chika ; Kagawa, Toyohiro ; Miwa, Kunihiro ; Yuasa, Kenji. / MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions. In: Oral Radiology. 2016 ; Vol. 32, No. 2. pp. 98-104.
@article{fc34c36c91f14a439367973b4cacce02,
title = "MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions",
abstract = "Objectives To compare magnetic resonance imaging (MRI) findings between patients with malignant lymphoma (ML) and squamous cell carcinoma (SCC) in the head and neck regions, and to show the characteristic findings for ML. Methods We analyzed 10 lesions in nine patients with ML and 25 lesions in 25 patients with SCC. Diffusion-weighted imaging, T1-weighted imaging, and T2-weighted imaging were performed for all lesions. We estimated the apparent diffusion coefficients (ADCs) with b-factors of 0, 500, and 1000 s/mm2, and obtained the means and standard deviations. In 29 cases, dynamic contrast-enhanced MRI (DCE-MRI) was performed and time–intensity curves were obtained. The peak time, maximum-to-initial ratio (MI ratio), end-to-maximum ratio, and end-to-initial ratio (EI ratio) were estimated. Receiver-operating characteristic analyses were performed to estimate the diagnostic power for these indices. Results The mean ADC for ML (0.762 ± 0.126 × 10−3 mm2/s) was significantly lower than that for SCC (1.24 ± 0.22 × 10-3 mm2/s, p < 0.0001). ML had a smaller MI ratio (2.13 ± 0.26) and smaller EI ratio (1.90 ± 0.29) than SCC (MI ratio: 2.46 ± 0.38, p = 0.033; EI ratio: 2.19 ± 0.29, p = 0.025). The area under the curve for the mean ADC (0.989) was higher than those for the MI ratio (0.779) and EI ratio (0.792).",
author = "Tomoko Shiraishi and Toru Chikui and Daisuke Inadomi and Marie Hashimoto and Chika Horio and Toyohiro Kagawa and Kunihiro Miwa and Kenji Yuasa",
year = "2016",
month = "7",
day = "23",
doi = "10.1007/s11282-015-0219-3",
language = "English",
volume = "32",
pages = "98--104",
journal = "Oral Radiology",
issn = "0911-6028",
publisher = "Springer Japan",
number = "2",

}

TY - JOUR

T1 - MRI findings of extranodal malignant lymphoma and squamous cell carcinoma in the head and neck regions

AU - Shiraishi, Tomoko

AU - Chikui, Toru

AU - Inadomi, Daisuke

AU - Hashimoto, Marie

AU - Horio, Chika

AU - Kagawa, Toyohiro

AU - Miwa, Kunihiro

AU - Yuasa, Kenji

PY - 2016/7/23

Y1 - 2016/7/23

N2 - Objectives To compare magnetic resonance imaging (MRI) findings between patients with malignant lymphoma (ML) and squamous cell carcinoma (SCC) in the head and neck regions, and to show the characteristic findings for ML. Methods We analyzed 10 lesions in nine patients with ML and 25 lesions in 25 patients with SCC. Diffusion-weighted imaging, T1-weighted imaging, and T2-weighted imaging were performed for all lesions. We estimated the apparent diffusion coefficients (ADCs) with b-factors of 0, 500, and 1000 s/mm2, and obtained the means and standard deviations. In 29 cases, dynamic contrast-enhanced MRI (DCE-MRI) was performed and time–intensity curves were obtained. The peak time, maximum-to-initial ratio (MI ratio), end-to-maximum ratio, and end-to-initial ratio (EI ratio) were estimated. Receiver-operating characteristic analyses were performed to estimate the diagnostic power for these indices. Results The mean ADC for ML (0.762 ± 0.126 × 10−3 mm2/s) was significantly lower than that for SCC (1.24 ± 0.22 × 10-3 mm2/s, p < 0.0001). ML had a smaller MI ratio (2.13 ± 0.26) and smaller EI ratio (1.90 ± 0.29) than SCC (MI ratio: 2.46 ± 0.38, p = 0.033; EI ratio: 2.19 ± 0.29, p = 0.025). The area under the curve for the mean ADC (0.989) was higher than those for the MI ratio (0.779) and EI ratio (0.792).

AB - Objectives To compare magnetic resonance imaging (MRI) findings between patients with malignant lymphoma (ML) and squamous cell carcinoma (SCC) in the head and neck regions, and to show the characteristic findings for ML. Methods We analyzed 10 lesions in nine patients with ML and 25 lesions in 25 patients with SCC. Diffusion-weighted imaging, T1-weighted imaging, and T2-weighted imaging were performed for all lesions. We estimated the apparent diffusion coefficients (ADCs) with b-factors of 0, 500, and 1000 s/mm2, and obtained the means and standard deviations. In 29 cases, dynamic contrast-enhanced MRI (DCE-MRI) was performed and time–intensity curves were obtained. The peak time, maximum-to-initial ratio (MI ratio), end-to-maximum ratio, and end-to-initial ratio (EI ratio) were estimated. Receiver-operating characteristic analyses were performed to estimate the diagnostic power for these indices. Results The mean ADC for ML (0.762 ± 0.126 × 10−3 mm2/s) was significantly lower than that for SCC (1.24 ± 0.22 × 10-3 mm2/s, p < 0.0001). ML had a smaller MI ratio (2.13 ± 0.26) and smaller EI ratio (1.90 ± 0.29) than SCC (MI ratio: 2.46 ± 0.38, p = 0.033; EI ratio: 2.19 ± 0.29, p = 0.025). The area under the curve for the mean ADC (0.989) was higher than those for the MI ratio (0.779) and EI ratio (0.792).

UR - http://www.scopus.com/inward/record.url?scp=84937696261&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84937696261&partnerID=8YFLogxK

U2 - 10.1007/s11282-015-0219-3

DO - 10.1007/s11282-015-0219-3

M3 - Article

AN - SCOPUS:84937696261

VL - 32

SP - 98

EP - 104

JO - Oral Radiology

JF - Oral Radiology

SN - 0911-6028

IS - 2

ER -