Mulberry anthracnose antagonists (iturins) produced by Bacillus amyloliquefaciens RC-2

Syuntaro Hiradate, Shigenobu Yoshida, Hajime Sugie, Hiroshi Yada, Yoshiharu Fujii

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Bacillus amyloliquefaciens strain RC-2 produced seven antifungal compounds (1-7) secreted into the culture filtrate. These compounds inhibited the development of mulberry anthracnose caused by the fungus, Colletotrichum dematium. Chemical structural analyses by NMR and FAB-MS revealed that all these compounds were iturins (cyclic peptides with the following sequence: L-Asn → D-Tyr → D-Asn → L-Gln → L-Pro → D-Asn → L-Ser → D-β-amino acid →) and compounds 1-6 are identical to iturins A-2-A-7, respectively. Compound 7 (iturin A-8) is a new iturin, which has a -(CH2)10CH(CH3)CH2CH3 group as a side chain in the β-amino acid in the molecule.

Original languageEnglish
Pages (from-to)693-698
Number of pages6
JournalPhytochemistry
Volume61
Issue number6
DOIs
Publication statusPublished - Nov 1 2002
Externally publishedYes

Fingerprint

Bacillus amyloliquefaciens
Morus
anthracnose
mulberries
Bacilli
antagonists
Colletotrichum
Amino Acids
Cyclic Peptides
Fungi
Colletotrichum dematium
Nuclear magnetic resonance
amino compounds
cyclic peptides
Molecules
amino acids
culture filtrates
fungi
iturin
iturin A

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

Cite this

Mulberry anthracnose antagonists (iturins) produced by Bacillus amyloliquefaciens RC-2. / Hiradate, Syuntaro; Yoshida, Shigenobu; Sugie, Hajime; Yada, Hiroshi; Fujii, Yoshiharu.

In: Phytochemistry, Vol. 61, No. 6, 01.11.2002, p. 693-698.

Research output: Contribution to journalArticle

Hiradate, Syuntaro ; Yoshida, Shigenobu ; Sugie, Hajime ; Yada, Hiroshi ; Fujii, Yoshiharu. / Mulberry anthracnose antagonists (iturins) produced by Bacillus amyloliquefaciens RC-2. In: Phytochemistry. 2002 ; Vol. 61, No. 6. pp. 693-698.
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