Multi-block and sequence-controlled polymerization of glycopolymers, and interaction with lectin

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Abstract

Polymers with controlled molecular weights and sequences are expected to be functional polymers. Synthesis of multi-block glycopolymers were investigated to fabricate the functional biopolymers. The glycopolymers having mannose side chain with polyacrylamide backbone were polymerized with acrylamide derivatives. We synthesized of multi-block glycopolymers consisting of up to 9 blocks. The polymerization was conducted with rapid reaction in high yield. The multi-block glycopolymers with glycoblock at the both ends were prepared with narrow molecular weights dispersity. Molecular recognition of glycopolymers were analysed using mannose recognition protein of concanavalin A.

Original languageEnglish
Article number110044
JournalEuropean Polymer Journal
Volume140
DOIs
Publication statusPublished - Nov 5 2020

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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