Multi-view learning over retinal thickness and visual sensitivity on glaucomatous eyes

Toshimitsu Uesaka, Kai Morino, Hiroki Sugiura, Taichi Kiwaki, Hiroshi Murata, Ryo Asaoka, Kenji Yamanishi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Dense measurements of visual-field, which is necessary to detect glaucoma, is known as very costly and labor intensive. Recently, measurement of retinal-thickness can be less costly than measurement of visual-field. Thus, it is sincerely desired that the retinalthickness could be transformed into visual-sensitivity data somehow. In this paper, we propose two novel methods to estimate the sensitivity of the visual-field with SITA-Standard mode 10-2 resolution using retinal-thickness data measured with optical coherence tomography (OCT). The first method called Affine-Structured Non-negative Matrix Factorization (ASNMF) which is able to cope with both the estimation of visual-field and the discovery of deep glaucoma knowledge. While, the second is based on Convolutional Neural Networks (CNNs) which demonstrates very high estimation performance. These methods are kinds of multi-view learning methods because they utilize visual-field and retinal thickness data simultaneously. We experimentally tested the performance of our methods from several perspectives. We found that ASNMF worked better for relatively small data size while CNNs did for relatively large data size. In addition, some clinical knowledge are discovered via ASNMF. To the best of our knowledge, this is the first paper to address the dense estimation of the visual-field based on the retinal-thickness data.

Original languageEnglish
Title of host publicationKDD 2017 - Proceedings of the 23rd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining
PublisherAssociation for Computing Machinery
Pages2041-2050
Number of pages10
ISBN (Electronic)9781450348874
DOIs
Publication statusPublished - Aug 13 2017
Event23rd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, KDD 2017 - Halifax, Canada
Duration: Aug 13 2017Aug 17 2017

Publication series

NameProceedings of the ACM SIGKDD International Conference on Knowledge Discovery and Data Mining
VolumePart F129685

Conference

Conference23rd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, KDD 2017
CountryCanada
CityHalifax
Period8/13/178/17/17

All Science Journal Classification (ASJC) codes

  • Software
  • Information Systems

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    Uesaka, T., Morino, K., Sugiura, H., Kiwaki, T., Murata, H., Asaoka, R., & Yamanishi, K. (2017). Multi-view learning over retinal thickness and visual sensitivity on glaucomatous eyes. In KDD 2017 - Proceedings of the 23rd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (pp. 2041-2050). (Proceedings of the ACM SIGKDD International Conference on Knowledge Discovery and Data Mining; Vol. Part F129685). Association for Computing Machinery. https://doi.org/10.1145/3097983.3098194