Abstract
Background: Preoperative prognostic information to select a treatment strategy is important especially in patients who need highly aggressive surgery, such as those with biliary cancer.We evaluated various prognostic factors and non-curative surgical factors using multidetector computed tomography (MDCT). Methods: We retrospectively analyzed 71 patients who underwent MDCT preoperatively and were scheduled for surgical resection of biliary cancer. For MDCT diagnosis, we used MDCT-based classification equivalent to the surgical and pathological classification of the Japanese Society of Biliary Surgery. We evaluated MDCT-related prognostic factors and non-curative surgical factors and compared these factors with pathological results. Results: MDCT-diagnosed category T (primary tumor invasion) included both prognostic factors and non-curative surgical factors but not category N (lymph node metastasis). Multivariate analysis identified MDCT-based suspected arterial invasion as an independent prognostic factor. In patients suspected of arterial invasion by MDCT, the 3-year overall survival rate was only 39% and the curative resection ratio was only 33%, because of the high positive surgical dissected margin. Conclusion: MDCT-based suspected arterial invasion is a predictor of poor prognosis after surgery for biliary cancer and represents a noncurative surgical factor associated with positive dissected margin.
| Original language | English |
|---|---|
| Pages (from-to) | 376-383 |
| Number of pages | 8 |
| Journal | Journal of Surgical Oncology |
| Volume | 101 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Apr 1 2010 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Surgery
- Oncology
Cite this
Multidetector computed tomography for preoperative prediction of postsurgical prognosis of patients with extrahepatic biliary cancer. / Kobayashi, Shogo; Nagano, Hiroaki; Marubashi, Shigeru; Wada, Hiroshi; Eguchi, Hidetoshi; Takeda, Yutaka; Tanemura, Masahiro; Kim, Tonsok; Doki, Yuichiro; Mori, Masaki.
In: Journal of Surgical Oncology, Vol. 101, No. 5, 01.04.2010, p. 376-383.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Multidetector computed tomography for preoperative prediction of postsurgical prognosis of patients with extrahepatic biliary cancer
AU - Kobayashi, Shogo
AU - Nagano, Hiroaki
AU - Marubashi, Shigeru
AU - Wada, Hiroshi
AU - Eguchi, Hidetoshi
AU - Takeda, Yutaka
AU - Tanemura, Masahiro
AU - Kim, Tonsok
AU - Doki, Yuichiro
AU - Mori, Masaki
PY - 2010/4/1
Y1 - 2010/4/1
N2 - Background: Preoperative prognostic information to select a treatment strategy is important especially in patients who need highly aggressive surgery, such as those with biliary cancer.We evaluated various prognostic factors and non-curative surgical factors using multidetector computed tomography (MDCT). Methods: We retrospectively analyzed 71 patients who underwent MDCT preoperatively and were scheduled for surgical resection of biliary cancer. For MDCT diagnosis, we used MDCT-based classification equivalent to the surgical and pathological classification of the Japanese Society of Biliary Surgery. We evaluated MDCT-related prognostic factors and non-curative surgical factors and compared these factors with pathological results. Results: MDCT-diagnosed category T (primary tumor invasion) included both prognostic factors and non-curative surgical factors but not category N (lymph node metastasis). Multivariate analysis identified MDCT-based suspected arterial invasion as an independent prognostic factor. In patients suspected of arterial invasion by MDCT, the 3-year overall survival rate was only 39% and the curative resection ratio was only 33%, because of the high positive surgical dissected margin. Conclusion: MDCT-based suspected arterial invasion is a predictor of poor prognosis after surgery for biliary cancer and represents a noncurative surgical factor associated with positive dissected margin.
AB - Background: Preoperative prognostic information to select a treatment strategy is important especially in patients who need highly aggressive surgery, such as those with biliary cancer.We evaluated various prognostic factors and non-curative surgical factors using multidetector computed tomography (MDCT). Methods: We retrospectively analyzed 71 patients who underwent MDCT preoperatively and were scheduled for surgical resection of biliary cancer. For MDCT diagnosis, we used MDCT-based classification equivalent to the surgical and pathological classification of the Japanese Society of Biliary Surgery. We evaluated MDCT-related prognostic factors and non-curative surgical factors and compared these factors with pathological results. Results: MDCT-diagnosed category T (primary tumor invasion) included both prognostic factors and non-curative surgical factors but not category N (lymph node metastasis). Multivariate analysis identified MDCT-based suspected arterial invasion as an independent prognostic factor. In patients suspected of arterial invasion by MDCT, the 3-year overall survival rate was only 39% and the curative resection ratio was only 33%, because of the high positive surgical dissected margin. Conclusion: MDCT-based suspected arterial invasion is a predictor of poor prognosis after surgery for biliary cancer and represents a noncurative surgical factor associated with positive dissected margin.
UR - http://www.scopus.com/inward/record.url?scp=77950539106&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950539106&partnerID=8YFLogxK
U2 - 10.1002/jso.21501
DO - 10.1002/jso.21501
M3 - Article
C2 - 20213730
AN - SCOPUS:77950539106
VL - 101
SP - 376
EP - 383
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
SN - 0022-4790
IS - 5
ER -