Abstract
Background: Preoperative prognostic information to select a treatment strategy is important especially in patients who need highly aggressive surgery, such as those with biliary cancer.We evaluated various prognostic factors and non-curative surgical factors using multidetector computed tomography (MDCT). Methods: We retrospectively analyzed 71 patients who underwent MDCT preoperatively and were scheduled for surgical resection of biliary cancer. For MDCT diagnosis, we used MDCT-based classification equivalent to the surgical and pathological classification of the Japanese Society of Biliary Surgery. We evaluated MDCT-related prognostic factors and non-curative surgical factors and compared these factors with pathological results. Results: MDCT-diagnosed category T (primary tumor invasion) included both prognostic factors and non-curative surgical factors but not category N (lymph node metastasis). Multivariate analysis identified MDCT-based suspected arterial invasion as an independent prognostic factor. In patients suspected of arterial invasion by MDCT, the 3-year overall survival rate was only 39% and the curative resection ratio was only 33%, because of the high positive surgical dissected margin. Conclusion: MDCT-based suspected arterial invasion is a predictor of poor prognosis after surgery for biliary cancer and represents a noncurative surgical factor associated with positive dissected margin.
Original language | English |
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Pages (from-to) | 376-383 |
Number of pages | 8 |
Journal | Journal of Surgical Oncology |
Volume | 101 |
Issue number | 5 |
DOIs | |
Publication status | Published - Apr 1 2010 |
All Science Journal Classification (ASJC) codes
- Surgery
- Oncology