Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer—: A Case Report

Shinichiro Fujishima, Yasushi Okada, Katsumi Irie, Takanari Kitazono, Yoshisuke Saku, Hidetsuna Utsunomiya, Shigetaka Sugihara, Seizo Sadoshima, Masatoshi Fujishima

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Abstract

A fifty-four-year-old woman died from multiple brain infarction and hemor rhage in the bilateral cerebrum, cerebellum, and brainstem, with renal infarc tion. She developed hematuria and transient blindness sixteen days before admission. Low-grade fever, heart murmur, and aortic valve vegetation on ul trasonic cardiography suggested infectious endocarditis. Autopsy study re vealed occult adenocarcinoma in the lung and nonbacterial thrombotic endocarditis, but infective endocarditis was not histologically confirmed. The patient was considered to be a rare case of nonbacterial thrombotic endocarditis who developed multiple small infarctions mainly in the brainstem and cerebel lum. Nonbacterial thrombotic endocarditis seems to be still an important dis ease as the embolic source, even if cryptic, of systemic thromboembolism.

Original languageEnglish
Pages (from-to)161-166
Number of pages6
JournalAngiology
Volume45
Issue number2
DOIs
Publication statusPublished - Jan 1 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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    Fujishima, S., Okada, Y., Irie, K., Kitazono, T., Saku, Y., Utsunomiya, H., Sugihara, S., Sadoshima, S., & Fujishima, M. (1994). Multiple Brain Infarction and Hemorrhage by Nonbacterial Thrombotic Endocarditis in Occult Lung Cancer—: A Case Report. Angiology, 45(2), 161-166. https://doi.org/10.1177/000331979404500213