Multiple dermatofibromas in a patient with systemic lupus erythematosus and sjögren's syndrome

Midori Tsutsumi, Takamichi Ito, Saho Kawahara, Yumi Yasukochi, Hiroshi Uchi, Masutaka Furue

Research output: Contribution to journalArticle

Abstract

Here we report a case of multiple dermatofibromas (MDF) arising in a patient with systemic lupus erythematosus (SLE) and Sjögren's syndrome. A 40-year-old woman with SLE and Sjögren's syndrome presented with a 5-year history of multiple cutaneous nodules. At the age of 33, she was diagnosed as having SLE and Sjögren's syndrome. Oral prednisolone was initiated and then tacrolimus was added at the age of 35. One month after the first administration of tacrolimus, she noticed a nodule on the chest. Similar nodules then appeared on the chest and limbs, eventually numbering 14 in total. Histologically, the nodule on the chest was composed of a proliferation of collagen bundles and spindle-shaped cells arranged in a storiform pattern in the dermis with reactive epidermal acanthosis, leading to the diagnosis of dermatofibroma. We have reviewed the comorbidity of MDF and internal diseases with special reference to SLE and Sjögren's syndrome.

Original languageEnglish
Pages (from-to)504-506
Number of pages3
JournalNishinihon Journal of Dermatology
Volume78
Issue number5
DOIs
Publication statusPublished - Jan 1 2016

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Benign Fibrous Histiocytoma
Systemic Lupus Erythematosus
Thorax
Tacrolimus
Dermis
Prednisolone
Comorbidity
Collagen
Extremities
Skin

All Science Journal Classification (ASJC) codes

  • Dermatology

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Multiple dermatofibromas in a patient with systemic lupus erythematosus and sjögren's syndrome. / Tsutsumi, Midori; Ito, Takamichi; Kawahara, Saho; Yasukochi, Yumi; Uchi, Hiroshi; Furue, Masutaka.

In: Nishinihon Journal of Dermatology, Vol. 78, No. 5, 01.01.2016, p. 504-506.

Research output: Contribution to journalArticle

Tsutsumi, Midori ; Ito, Takamichi ; Kawahara, Saho ; Yasukochi, Yumi ; Uchi, Hiroshi ; Furue, Masutaka. / Multiple dermatofibromas in a patient with systemic lupus erythematosus and sjögren's syndrome. In: Nishinihon Journal of Dermatology. 2016 ; Vol. 78, No. 5. pp. 504-506.
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AU - Uchi, Hiroshi

AU - Furue, Masutaka

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