Multiple pregnancy, short cervix, part-time worker, steroid use, low educational level and male fetus are risk factors for preterm birth in Japan: A multicenter, prospective study

Arihiro Shiozaki, Satoshi Yoneda, Masao Nakabayashi, Yoshiharu Takeda, Satoru Takeda, Motoi Sugimura, Koyo Yoshida, Atsushi Tajima, Mami Manabe, Kozo Akagi, Shoko Nakagawa, Katsuhiko Tada, Noriaki Imafuku, Masanobu Ogawa, Tomoya Mizunoe, Naohiro Kanayama, Hiroaki Itoh, Shigeki Minoura, Mitsuharu Ogino, Shigeru Saito

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Aim: To examine the relationship between preterm birth and socioeconomic factors, past history, cervical length, cervical interleukin-8, bacterial vaginosis, underlying diseases, use of medication, employment status, sex of the fetus and multiple pregnancy. Methods: In a multicenter, prospective, observational study, 1810 Japanese women registering their future delivery were enrolled at 8+0 to 12+6 weeks of gestation. Data on cervical length and delivery were obtained from 1365 pregnant women. Multivariate logistic regression analysis was performed. Results: Short cervical length, steroid use, multiple pregnancy and male fetus were risk factors for preterm birth before 34 weeks of gestation. Multiple pregnancy, low educational level, short cervical length and part-timer were risk factors for preterm birth before 37 weeks of gestation. Conclusion: Multiple pregnancy and cervical shortening at 20-24 weeks of gestation was a stronger risk factor for preterm birth. Any pregnant woman being part-time employee or low educational level, having a male fetus and requiring steroid treatment should be watched for the development of preterm birth.

Original languageEnglish
Pages (from-to)53-61
Number of pages9
JournalJournal of Obstetrics and Gynaecology Research
Volume40
Issue number1
DOIs
Publication statusPublished - Jan 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

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