Multiple receptor proteins for sweet taste in Drosophila discriminated by papain treatment

Teiichi Tanimura, Ichiro Shimada

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Treatment of the labellar chemosensory setae of the fruit fly, Drosophila melanogaster, with 0.1 % papain for 3 min induced a complete elimination of the taste nerve response to fructose (Fig. 1). Responses to other sugars examined were not affected (Table 1). Responses to 20 mM LiCl and 0.1 M NaCl also remained unchanged by the treatment. The experiment on the time-dependency of the papain treatment showed a clear difference in the proteasesensitivity between the response to fructose and to glucose and sucrose (Fig. 2). The treatment with 0.005% trypsin for 3 min produced the same results. The response to fructose which was eliminated with the papain treatment, was restored after 3 hrs. These findings reveal the presence of a specific receptor site for fructose and its protease-sensitive nature and suggest the involvement of multiple receptor proteins in the sugar receptor of Drosophila.

Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalJournal of Comparative Physiology □ A
Volume141
Issue number2
DOIs
Publication statusPublished - Jun 1 1981

Fingerprint

protein sweeteners
Papain
papain
Drosophila
fructose
sugar
Fructose
receptors
protein
sucrose
glucose
Proteins
fruit
sugars
setae (animal)
Therapeutics
Sensilla
fruit flies
trypsin
Drosophila melanogaster

All Science Journal Classification (ASJC) codes

  • Physiology
  • Ecology, Evolution, Behavior and Systematics
  • Animal Science and Zoology
  • Behavioral Neuroscience

Cite this

Multiple receptor proteins for sweet taste in Drosophila discriminated by papain treatment. / Tanimura, Teiichi; Shimada, Ichiro.

In: Journal of Comparative Physiology □ A, Vol. 141, No. 2, 01.06.1981, p. 265-269.

Research output: Contribution to journalArticle

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