Multivariate analysis of long-term results after an axillobifemoral and aortobifemoral bypass in patients with aortoiliac occlusive disease

T. Onohara, K. Komori, M. Kume, M. Ishida, S. Ohta, K. Takeuchi, takuya matsumoto, K. Sugimachi

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Abstract

Background. Controversy still remains regarding the long-term results and indications for axillofemoral bypass (AxFB). A comparison of axillobifemoral bypass (AxBFB) and aortobifemoral bypass (ABFB) was thus conducted to determine whether AxFB is an acceptable alternative vascular procedure to anatomic bypass for high-risk patients. Methods. Sixty-three patients who underwent a total of 25 AxBFBs and 38 ABFBs for aortoiliac occlusive disease were reviewed retrospectively, and both univariate and multivarate analyses were performed. Results. The overall survival was 82.8% at five years. A univariate analysis revealed significantly lower survival rates for patients with limb-threatening ischemia, coronary disease, and cerebrovascular disease. A multivariate analysis disclosed no significant factors influencing survival rates. The overall primary patency was 79.8% at five years. The primary patency rates for AxBFB (67.7% at five years) were significantly lower than for ABFB (88.5% at five years) based on a univariate analysis (p=0.0045). In addition, the secondary patency rates for AxBFB (80.3% at five years) were significantly lower than for ABFB (96.5% at five years, p=0.0025). A multivariate analysis disclosed significantly lower primary patency rates for grafts with a higher angiographic outflow score and simultaneous infrainguinal reconstructive procedures, but the differences between AxBFB and ABFB were not significant. Conclusions. The survival and primary patency for the AxBFB group were both inferior to the ABFB group, however a multivarate analysis disclosed no significant differences between the two groups. Poor femoral runoff and the presence of synchronous infrainguinal reconstructive procedures significantly affected graft patency, and these factors modulated the patency of AxBFB. AxBFB for aortoiliac occlusive disease is therefore considered to be an acceptable procedure in appropriately selected patients.

Original languageEnglish
Pages (from-to)905-910
Number of pages6
JournalJournal of Cardiovascular Surgery
Volume41
Issue number6
Publication statusPublished - Dec 1 2000

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Multivariate Analysis
Survival Rate
Transplants
Cerebrovascular Disorders
Survival
Thigh
Coronary Disease
Blood Vessels
Ischemia
Extremities

All Science Journal Classification (ASJC) codes

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Onohara, T., Komori, K., Kume, M., Ishida, M., Ohta, S., Takeuchi, K., ... Sugimachi, K. (2000). Multivariate analysis of long-term results after an axillobifemoral and aortobifemoral bypass in patients with aortoiliac occlusive disease. Journal of Cardiovascular Surgery, 41(6), 905-910.

Multivariate analysis of long-term results after an axillobifemoral and aortobifemoral bypass in patients with aortoiliac occlusive disease. / Onohara, T.; Komori, K.; Kume, M.; Ishida, M.; Ohta, S.; Takeuchi, K.; matsumoto, takuya; Sugimachi, K.

In: Journal of Cardiovascular Surgery, Vol. 41, No. 6, 01.12.2000, p. 905-910.

Research output: Contribution to journalArticle

Onohara, T, Komori, K, Kume, M, Ishida, M, Ohta, S, Takeuchi, K, matsumoto, T & Sugimachi, K 2000, 'Multivariate analysis of long-term results after an axillobifemoral and aortobifemoral bypass in patients with aortoiliac occlusive disease', Journal of Cardiovascular Surgery, vol. 41, no. 6, pp. 905-910.
Onohara, T. ; Komori, K. ; Kume, M. ; Ishida, M. ; Ohta, S. ; Takeuchi, K. ; matsumoto, takuya ; Sugimachi, K. / Multivariate analysis of long-term results after an axillobifemoral and aortobifemoral bypass in patients with aortoiliac occlusive disease. In: Journal of Cardiovascular Surgery. 2000 ; Vol. 41, No. 6. pp. 905-910.
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abstract = "Background. Controversy still remains regarding the long-term results and indications for axillofemoral bypass (AxFB). A comparison of axillobifemoral bypass (AxBFB) and aortobifemoral bypass (ABFB) was thus conducted to determine whether AxFB is an acceptable alternative vascular procedure to anatomic bypass for high-risk patients. Methods. Sixty-three patients who underwent a total of 25 AxBFBs and 38 ABFBs for aortoiliac occlusive disease were reviewed retrospectively, and both univariate and multivarate analyses were performed. Results. The overall survival was 82.8{\%} at five years. A univariate analysis revealed significantly lower survival rates for patients with limb-threatening ischemia, coronary disease, and cerebrovascular disease. A multivariate analysis disclosed no significant factors influencing survival rates. The overall primary patency was 79.8{\%} at five years. The primary patency rates for AxBFB (67.7{\%} at five years) were significantly lower than for ABFB (88.5{\%} at five years) based on a univariate analysis (p=0.0045). In addition, the secondary patency rates for AxBFB (80.3{\%} at five years) were significantly lower than for ABFB (96.5{\%} at five years, p=0.0025). A multivariate analysis disclosed significantly lower primary patency rates for grafts with a higher angiographic outflow score and simultaneous infrainguinal reconstructive procedures, but the differences between AxBFB and ABFB were not significant. Conclusions. The survival and primary patency for the AxBFB group were both inferior to the ABFB group, however a multivarate analysis disclosed no significant differences between the two groups. Poor femoral runoff and the presence of synchronous infrainguinal reconstructive procedures significantly affected graft patency, and these factors modulated the patency of AxBFB. AxBFB for aortoiliac occlusive disease is therefore considered to be an acceptable procedure in appropriately selected patients.",
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T1 - Multivariate analysis of long-term results after an axillobifemoral and aortobifemoral bypass in patients with aortoiliac occlusive disease

AU - Onohara, T.

AU - Komori, K.

AU - Kume, M.

AU - Ishida, M.

AU - Ohta, S.

AU - Takeuchi, K.

AU - matsumoto, takuya

AU - Sugimachi, K.

PY - 2000/12/1

Y1 - 2000/12/1

N2 - Background. Controversy still remains regarding the long-term results and indications for axillofemoral bypass (AxFB). A comparison of axillobifemoral bypass (AxBFB) and aortobifemoral bypass (ABFB) was thus conducted to determine whether AxFB is an acceptable alternative vascular procedure to anatomic bypass for high-risk patients. Methods. Sixty-three patients who underwent a total of 25 AxBFBs and 38 ABFBs for aortoiliac occlusive disease were reviewed retrospectively, and both univariate and multivarate analyses were performed. Results. The overall survival was 82.8% at five years. A univariate analysis revealed significantly lower survival rates for patients with limb-threatening ischemia, coronary disease, and cerebrovascular disease. A multivariate analysis disclosed no significant factors influencing survival rates. The overall primary patency was 79.8% at five years. The primary patency rates for AxBFB (67.7% at five years) were significantly lower than for ABFB (88.5% at five years) based on a univariate analysis (p=0.0045). In addition, the secondary patency rates for AxBFB (80.3% at five years) were significantly lower than for ABFB (96.5% at five years, p=0.0025). A multivariate analysis disclosed significantly lower primary patency rates for grafts with a higher angiographic outflow score and simultaneous infrainguinal reconstructive procedures, but the differences between AxBFB and ABFB were not significant. Conclusions. The survival and primary patency for the AxBFB group were both inferior to the ABFB group, however a multivarate analysis disclosed no significant differences between the two groups. Poor femoral runoff and the presence of synchronous infrainguinal reconstructive procedures significantly affected graft patency, and these factors modulated the patency of AxBFB. AxBFB for aortoiliac occlusive disease is therefore considered to be an acceptable procedure in appropriately selected patients.

AB - Background. Controversy still remains regarding the long-term results and indications for axillofemoral bypass (AxFB). A comparison of axillobifemoral bypass (AxBFB) and aortobifemoral bypass (ABFB) was thus conducted to determine whether AxFB is an acceptable alternative vascular procedure to anatomic bypass for high-risk patients. Methods. Sixty-three patients who underwent a total of 25 AxBFBs and 38 ABFBs for aortoiliac occlusive disease were reviewed retrospectively, and both univariate and multivarate analyses were performed. Results. The overall survival was 82.8% at five years. A univariate analysis revealed significantly lower survival rates for patients with limb-threatening ischemia, coronary disease, and cerebrovascular disease. A multivariate analysis disclosed no significant factors influencing survival rates. The overall primary patency was 79.8% at five years. The primary patency rates for AxBFB (67.7% at five years) were significantly lower than for ABFB (88.5% at five years) based on a univariate analysis (p=0.0045). In addition, the secondary patency rates for AxBFB (80.3% at five years) were significantly lower than for ABFB (96.5% at five years, p=0.0025). A multivariate analysis disclosed significantly lower primary patency rates for grafts with a higher angiographic outflow score and simultaneous infrainguinal reconstructive procedures, but the differences between AxBFB and ABFB were not significant. Conclusions. The survival and primary patency for the AxBFB group were both inferior to the ABFB group, however a multivarate analysis disclosed no significant differences between the two groups. Poor femoral runoff and the presence of synchronous infrainguinal reconstructive procedures significantly affected graft patency, and these factors modulated the patency of AxBFB. AxBFB for aortoiliac occlusive disease is therefore considered to be an acceptable procedure in appropriately selected patients.

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