Dynamics of living cell surface, hepatocyte was measured with an atomic force microscope (AFM). A thermal fluctuation spectroscopy, in which the thermal noise of cantilever is monitored to estimate the mechanical properties of sample surfaces, was for the first time applied to living cells. The power spectrum of cantilevers was analyzed using a harmonic oscillator with memory function of the friction coefficient. The results showed that the friction coefficient decreased with increasing the frequency in the range of 1-20 kHz, indicating the dispersion of the cell surface friction coefficient in the microsecond time domain.
|Number of pages||1|
|Publication status||Published - Oct 19 2006|
|Event||55th SPSJ Annual Meeting - Nagoya, Japan|
Duration: May 24 2006 → May 26 2006
|Other||55th SPSJ Annual Meeting|
|Period||5/24/06 → 5/26/06|
All Science Journal Classification (ASJC) codes