Nano-dynamics of living cell surface by AFM

Takaharu Okajima, Masaru Tanaka, Shusaku Tsukiyama, Sadaaki Yamamoto, Masatsugu Shimomura, Hiroshi Tokumoto

Research output: Contribution to conferencePaper

Abstract

Dynamics of living cell surface, hepatocyte was measured with an atomic force microscope (AFM). A thermal fluctuation spectroscopy, in which the thermal noise of cantilever is monitored to estimate the mechanical properties of sample surfaces, was for the first time applied to living cells. The power spectrum of cantilevers was analyzed using a harmonic oscillator with memory function of the friction coefficient. The results showed that the friction coefficient decreased with increasing the frequency in the range of 1-20 kHz, indicating the dispersion of the cell surface friction coefficient in the microsecond time domain.

Original languageEnglish
Number of pages1
Publication statusPublished - Oct 19 2006
Externally publishedYes
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: May 24 2006May 26 2006

Other

Other55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period5/24/065/26/06

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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  • Cite this

    Okajima, T., Tanaka, M., Tsukiyama, S., Yamamoto, S., Shimomura, M., & Tokumoto, H. (2006). Nano-dynamics of living cell surface by AFM. Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.