Nanobiodevices for single DNA and cell analysis

Noritada Kaji, Yoshinobu Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nanopore-based DNA sequencing is an emerging technology that may soon overcome even the current next-generation sequencing from the viewpoint of DNA sequencing cost and throughput. In this paper, we will show that recent advances of the "pretreatment" process using various nanostructures such as nanopillars, nanowires, and nanoslits structures inside microchannel. In addition, another type of micro and nanostructures such as micro and nanometer-scale chamber array on a chip becomes a powerful new tool for bioanalysis since it could stochastically capture and measure biomolecules at a single molecule level. The applications of these chamber array structures for single cell analysis will be also described.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages264-266
Number of pages3
ISBN (Electronic)9780979806476
Publication statusPublished - Jan 1 2014
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/1410/30/14

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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