Abstract
Many biological systems, including protein complexes, are natural nanostructures. To better understand these structures and to monitor them in real time, it is becoming increasingly important to develop nanometer-scale signaling markers. Single-molecule methods will play a major role in elucidating the role of all proteins and their mutual interactions in a given organism. Fluorescent semiconductor nanocrystals, known as quantum dots, have several advantages of optical and chemical features over the traditional fluorescent labels. These features make them desirable for long-term stability and simultaneous detection of multiple signals. Here, we review current approaches to developing a biological application for quantum dots.
| Original language | English |
|---|---|
| Pages (from-to) | 565-572 |
| Number of pages | 8 |
| Journal | Expert Review of Proteomics |
| Volume | 4 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 1 2007 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
Cite this
Nanobiotechnology : Quantum dots in bioimaging. / Zhang, Yong; Kaji, Noritada; Tokeshi, Manabu; Baba, Yoshinobu.
In: Expert Review of Proteomics, Vol. 4, No. 4, 01.08.2007, p. 565-572.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Nanobiotechnology
T2 - Quantum dots in bioimaging
AU - Zhang, Yong
AU - Kaji, Noritada
AU - Tokeshi, Manabu
AU - Baba, Yoshinobu
PY - 2007/8/1
Y1 - 2007/8/1
N2 - Many biological systems, including protein complexes, are natural nanostructures. To better understand these structures and to monitor them in real time, it is becoming increasingly important to develop nanometer-scale signaling markers. Single-molecule methods will play a major role in elucidating the role of all proteins and their mutual interactions in a given organism. Fluorescent semiconductor nanocrystals, known as quantum dots, have several advantages of optical and chemical features over the traditional fluorescent labels. These features make them desirable for long-term stability and simultaneous detection of multiple signals. Here, we review current approaches to developing a biological application for quantum dots.
AB - Many biological systems, including protein complexes, are natural nanostructures. To better understand these structures and to monitor them in real time, it is becoming increasingly important to develop nanometer-scale signaling markers. Single-molecule methods will play a major role in elucidating the role of all proteins and their mutual interactions in a given organism. Fluorescent semiconductor nanocrystals, known as quantum dots, have several advantages of optical and chemical features over the traditional fluorescent labels. These features make them desirable for long-term stability and simultaneous detection of multiple signals. Here, we review current approaches to developing a biological application for quantum dots.
UR - http://www.scopus.com/inward/record.url?scp=34548331976&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548331976&partnerID=8YFLogxK
U2 - 10.1586/14789450.4.4.565
DO - 10.1586/14789450.4.4.565
M3 - Review article
C2 - 17705713
AN - SCOPUS:34548331976
VL - 4
SP - 565
EP - 572
JO - Expert Review of Proteomics
JF - Expert Review of Proteomics
SN - 1478-9450
IS - 4
ER -