Nanodevices for studying nano-pathophysiology

Horacio Cabral, Kanjiro Miyata, Akihiro Kishimura

Research output: Contribution to journalReview article

23 Citations (Scopus)

Abstract

Nano-scaled devices are a promising platform for specific detection of pathological targets, facilitating the analysis of biological tissues in real-time, while improving the diagnostic approaches and the efficacy of therapies. Herein, we review nanodevice approaches, including liposomes, nanoparticles and polymeric nanoassemblies, such as polymeric micelles and vesicles, which can precisely control their structure and functions for specifically interacting with cells and tissues. These systems have been successfully used for the selective delivery of reporter and therapeutic agents to specific tissues with controlled cellular and subcellular targeting of biomolecules and programmed operation inside the body, suggesting a high potential for developing the analysis for nano-pathophysiology.

Original languageEnglish
Pages (from-to)35-52
Number of pages18
JournalAdvanced Drug Delivery Reviews
Volume74
DOIs
Publication statusPublished - Jul 30 2014

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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