Nanopillar chips arranged in tilted array pattern for fast separation of DNA and proteins

Takao Yasui, Noritada Kaji, Mohamad Reza Mohamadi, Ryo Ogawa, Shingi Hashioka, Manabu Tokeshi, Yasuhiro Horiike, Yoshinobu Baba

Research output: Contribution to conferencePaper

3 Citations (Scopus)

Abstract

In this paper, EOF mesurement and biomolecular separation (21-340 kDa in proteins, 1-48.5 kbp in DNA) were carefully studied by using nanopillar chips arranged in tilted array pattern with 100-nm spacing. We revealed that the nanopillar chips had an intrinstic function to suppress electro-osmotic flow (EOF), and as a result, DNA and SDS-protein complexes could be separated without any sieving matrices and surface coatings.

Original languageEnglish
Pages432-434
Number of pages3
Publication statusPublished - 2008
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: Oct 12 2008Oct 16 2008

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period10/12/0810/16/08

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Yasui, T., Kaji, N., Mohamadi, M. R., Ogawa, R., Hashioka, S., Tokeshi, M., Horiike, Y., & Baba, Y. (2008). Nanopillar chips arranged in tilted array pattern for fast separation of DNA and proteins. 432-434. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.