Nanoscale evaluation of lubricity on well-defined polymer brush surfaces using QCM-D and AFM

Kazuhiko Kitano, Yuuki Inoue, Ryosuke Matsuno, Madoka Takai, Kazuhiko Ishihara

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

For preparing a "highly lubricated biointerface", which has both excellent lubricity and biocompatibility, we investigated the factors responsible for resistance to friction during polymer grafting. We prepared poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), poly(2-hydroxyethyl methacrylate) (PHEMA), and poly(methyl methacrylate) (PMMA) brush layers with high graft density and well-controlled thickness using atom transfer radical polymerization (ATRP). We measured the water absorptivity in the polymer brush layers and the viscoelasticity of the polymer-hydrated layers using a quartz crystal microbalance with dissipation monitoring (QCM-D) measurements. The PMPC brush layer had the highest water absorptivity, while the PMPC-hydrated layer had the highest fluidity. The friction properties of the polymer brush layers were determined in air, water, and toluene by atomic force microscopy (AFM). The friction on each polymer brush decreased only when a good solvent was chosen for each polymer. In conclusion, the brush layer possessing high water absorptivity and fluidity in water contributes to reduce friction. PMPC grafting is an effective and promising method for obtaining highly lubricated biointerfaces.

Original languageEnglish
Pages (from-to)350-357
Number of pages8
JournalColloids and Surfaces B: Biointerfaces
Volume74
Issue number1
DOIs
Publication statusPublished - Nov 1 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Surfaces and Interfaces
  • Physical and Theoretical Chemistry
  • Colloid and Surface Chemistry

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