Nanowires for early cancer and diabetes diagnosis via micro-RNA detection in urine extracellular vesicles

T. Yasui, D. Takeshita, T. Yanagida, N. Kaji, M. Kanai, K. Nagashima, H. Yukawa, T. Kawai, Y. Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Inorganic nanowires recently show their great promise for analyzing cells or intracellular components due to the nanowires feature of a stealth effect against cell surfaces [1]. Here we showed a novel usability of the nanowires to achieve an efficient capture of extracellular vesicles, which surfaces is similar to the cell surfaces, and early diagnosis based on the vesicles microRNAs. Our methodology could achieve extracellular vesicles capture in urine over 95% within 40 min, and detect cancer- and type 2 diabetes-related microRNAs from urine samples.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages108-109
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - Jan 1 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

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All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Yasui, T., Takeshita, D., Yanagida, T., Kaji, N., Kanai, M., Nagashima, K., ... Baba, Y. (2016). Nanowires for early cancer and diabetes diagnosis via micro-RNA detection in urine extracellular vesicles. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 108-109). (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016). Chemical and Biological Microsystems Society.